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Murcko scaffold

2-(2,3-Dioxo-4-phenylpyrazin-1-yl)-N-phenylacetamide scaffold

177 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
177
With full pages
4
Scaffold SMILES

O=C(Cn1ccn(-c2ccccc2)c(=O)c1=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(2,3-Dioxo-4-phenylpyrazin-1-yl)-N-phenylacetamide page
Murcko scaffold O=C(Cn1ccn(-c2ccccc2)c(=O)c1=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 177 chemicals

2-(2,3-Dioxo-4-phenylpyrazin-1-yl)-N-phenylacetamide chemical structure, C18H15N3O3, CAS 899213-26-4
2-(2,3-Dioxo-4-phenylpyrazin-1-yl)-N-phenylacetamide
CAS 899213-26-4C18H15N3O3
2-(2,3-Dioxo-4-phenylpyrazin-1-yl)-N-(4-ethylphenyl)acetamide chemical structure, C20H19N3O3, CAS 899214-50-7
2-(2,3-Dioxo-4-phenylpyrazin-1-yl)-N-(4-ethylphenyl)acetamide
CAS 899214-50-7C20H19N3O3
2-(2,3-Dioxo-4-phenylpyrazin-1-yl)-N-(4-methylphenyl)acetamide chemical structure, C19H17N3O3, CAS 899214-51-8
2-(2,3-Dioxo-4-phenylpyrazin-1-yl)-N-(4-methylphenyl)acetamide
CAS 899214-51-8C19H17N3O3
N-(3,4-Dimethylphenyl)-2-(2,3-dioxo-4-phenylpyrazin-1-yl)acetamide chemical structure, C20H19N3O3, CAS 899214-52-9
N-(3,4-Dimethylphenyl)-2-(2,3-dioxo-4-phenylpyrazin-1-yl)acetamide
CAS 899214-52-9C20H19N3O3
N-(3-Chloro-4-methoxyphenyl)-2-(2,3-dioxo-4-phenylpyrazin-1-yl)acetamide chemical structure, C19H16ClN3O4, CAS 899214-53-0
N-(3-Chloro-4-methoxyphenyl)-2-(2,3-dioxo-4-phenylpyrazin-1-yl)acetamide
CAS 899214-53-0C19H16ClN3O4
2-(2,3-Dioxo-4-phenylpyrazin-1-yl)-N-(3-methylphenyl)acetamide chemical structure, C19H17N3O3, CAS 899214-54-1
2-(2,3-Dioxo-4-phenylpyrazin-1-yl)-N-(3-methylphenyl)acetamide
CAS 899214-54-1C19H17N3O3
N-(5-Chloro-2-methoxyphenyl)-2-(2,3-dioxo-4-phenylpyrazin-1-yl)acetamide chemical structure, C19H16ClN3O4, CAS 899213-25-3
N-(5-Chloro-2-methoxyphenyl)-2-(2,3-dioxo-4-phenylpyrazin-1-yl)acetamide
CAS 899213-25-3C19H16ClN3O4
N-(3,5-Dimethoxyphenyl)-2-(2,3-dioxo-4-phenylpyrazin-1-yl)acetamide chemical structure, C20H19N3O5, CAS 899213-27-5
N-(3,5-Dimethoxyphenyl)-2-(2,3-dioxo-4-phenylpyrazin-1-yl)acetamide
CAS 899213-27-5C20H19N3O5
2-[4-(3-Chlorophenyl)-2,3-dioxopyrazin-1-yl]-N-(3,4-dimethylphenyl)acetamide chemical structure, C20H18ClN3O3, CAS 895651-13-5
2-[4-(3-Chlorophenyl)-2,3-dioxopyrazin-1-yl]-N-(3,4-dimethylphenyl)acetamide
CAS 895651-13-5C20H18ClN3O3
N-(3-Chlorophenyl)-2-[4-(4-methoxyphenyl)-2,3-dioxopyrazin-1-yl]acetamide chemical structure, C19H16ClN3O4, CAS 899942-51-9
N-(3-Chlorophenyl)-2-[4-(4-methoxyphenyl)-2,3-dioxopyrazin-1-yl]acetamide
CAS 899942-51-9C19H16ClN3O4
N-(4-Ethylphenyl)-2-[4-(4-methoxyphenyl)-2,3-dioxopyrazin-1-yl]acetamide chemical structure, C21H21N3O4, CAS 891867-00-8
N-(4-Ethylphenyl)-2-[4-(4-methoxyphenyl)-2,3-dioxopyrazin-1-yl]acetamide
CAS 891867-00-8C21H21N3O4
N-(2,4-Dimethylphenyl)-2-[4-(4-methoxyphenyl)-2,3-dioxopyrazin-1-yl]acetamide chemical structure, C21H21N3O4, CAS 891867-14-4
N-(2,4-Dimethylphenyl)-2-[4-(4-methoxyphenyl)-2,3-dioxopyrazin-1-yl]acetamide
CAS 891867-14-4C21H21N3O4
2-[4-(4-Methoxyphenyl)-2,3-dioxopyrazin-1-yl]-N-phenylacetamide chemical structure, C19H17N3O4, CAS 891867-15-5
2-[4-(4-Methoxyphenyl)-2,3-dioxopyrazin-1-yl]-N-phenylacetamide
CAS 891867-15-5C19H17N3O4
N-(3,4-Dimethoxyphenyl)-2-[4-(4-methoxyphenyl)-2,3-dioxopyrazin-1-yl]acetamide chemical structure, C21H21N3O6, CAS 891867-20-2
N-(3,4-Dimethoxyphenyl)-2-[4-(4-methoxyphenyl)-2,3-dioxopyrazin-1-yl]acetamide
CAS 891867-20-2C21H21N3O6
N-(5-Chloro-2-methoxyphenyl)-2-[4-(4-fluorophenyl)-2,3-dioxopyrazin-1-yl]acetamide chemical structure, C19H15ClFN3O4, CAS 904523-93-9
N-(5-Chloro-2-methoxyphenyl)-2-[4-(4-fluorophenyl)-2,3-dioxopyrazin-1-yl]acetamide
CAS 904523-93-9C19H15ClFN3O4
N-(2,4-Dimethylphenyl)-2-[4-(4-fluorophenyl)-2,3-dioxopyrazin-1-yl]acetamide chemical structure, C20H18FN3O3, CAS 904523-95-1
N-(2,4-Dimethylphenyl)-2-[4-(4-fluorophenyl)-2,3-dioxopyrazin-1-yl]acetamide
CAS 904523-95-1C20H18FN3O3
2-[4-(4-Fluorophenyl)-2,3-dioxopyrazin-1-yl]-N-[3-(trifluoromethyl)phenyl]acetamide chemical structure, C19H13F4N3O3, CAS 886886-43-7
2-[4-(4-Fluorophenyl)-2,3-dioxopyrazin-1-yl]-N-[3-(trifluoromethyl)phenyl]acetamide
CAS 886886-43-7C19H13F4N3O3
N-(2-Chlorophenyl)-2-[4-(3,4-dimethoxyphenyl)-2,3-dioxopyrazin-1-yl]acetamide chemical structure, C20H18ClN3O5, CAS 898428-76-7
N-(2-Chlorophenyl)-2-[4-(3,4-dimethoxyphenyl)-2,3-dioxopyrazin-1-yl]acetamide
CAS 898428-76-7C20H18ClN3O5
N-(2-Chlorophenyl)-2-[4-(2-ethoxyphenyl)-2,3-dioxopyrazin-1-yl]acetamide chemical structure, C20H18ClN3O4, CAS 898409-22-8
N-(2-Chlorophenyl)-2-[4-(2-ethoxyphenyl)-2,3-dioxopyrazin-1-yl]acetamide
CAS 898409-22-8C20H18ClN3O4
2-[4-(3-Chloro-4-fluorophenyl)-2,3-dioxopyrazin-1-yl]-N-(4-methylphenyl)acetamide chemical structure, C19H15ClFN3O3, CAS 898428-78-9
2-[4-(3-Chloro-4-fluorophenyl)-2,3-dioxopyrazin-1-yl]-N-(4-methylphenyl)acetamide
CAS 898428-78-9C19H15ClFN3O3
2-[4-(5-Chloro-2-methoxyphenyl)-2,3-dioxopyrazin-1-yl]-N-(4-methylphenyl)acetamide chemical structure, C20H18ClN3O4, CAS 898463-63-3
2-[4-(5-Chloro-2-methoxyphenyl)-2,3-dioxopyrazin-1-yl]-N-(4-methylphenyl)acetamide
CAS 898463-63-3C20H18ClN3O4
2-[4-(3-Ethylphenyl)-2,3-dioxopyrazin-1-yl]-N-[2-(trifluoromethyl)phenyl]acetamide chemical structure, C21H18F3N3O3, CAS 898428-80-3
2-[4-(3-Ethylphenyl)-2,3-dioxopyrazin-1-yl]-N-[2-(trifluoromethyl)phenyl]acetamide
CAS 898428-80-3C21H18F3N3O3
2-[4-(3-Fluoro-4-methylphenyl)-2,3-dioxopyrazin-1-yl]-N-(2-methoxyphenyl)acetamide chemical structure, C20H18FN3O4, CAS 898409-26-2
2-[4-(3-Fluoro-4-methylphenyl)-2,3-dioxopyrazin-1-yl]-N-(2-methoxyphenyl)acetamide
CAS 898409-26-2C20H18FN3O4
2-[4-(5-Chloro-2-methylphenyl)-2,3-dioxopyrazin-1-yl]-N-(2-methoxyphenyl)acetamide chemical structure, C20H18ClN3O4, CAS 898428-82-5
2-[4-(5-Chloro-2-methylphenyl)-2,3-dioxopyrazin-1-yl]-N-(2-methoxyphenyl)acetamide
CAS 898428-82-5C20H18ClN3O4