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Murcko scaffold

Ring system with 3 rings and 22 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
11
With full pages
0
Scaffold SMILES

O=C(C=Cc1ccc(-c2ccccc2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccc(-c2ccccc2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

2-Propen-1-one, 3-[1,1'-biphenyl]-4-yl-1-(4-nitrophenyl)- chemical structure, C21H15NO3, CAS 89807-55-6
2-Propen-1-one, 3-[1,1'-biphenyl]-4-yl-1-(4-nitrophenyl)-
CAS 89807-55-6C21H15NO3
3-([1,1'-Biphenyl]-4-yl)-1-(4-methylphenyl)prop-2-en-1-one chemical structure, C22H18O, CAS 36635-70-8
3-([1,1'-Biphenyl]-4-yl)-1-(4-methylphenyl)prop-2-en-1-one
CAS 36635-70-8C22H18O
2-Propen-1-one, 3-[1,1'-biphenyl]-4-yl-1-(4-methoxyphenyl)- chemical structure, C22H18O2, CAS 6552-69-8
2-Propen-1-one, 3-[1,1'-biphenyl]-4-yl-1-(4-methoxyphenyl)-
CAS 6552-69-8C22H18O2
1-(2-Bromophenyl)-3-(4-phenylphenyl)prop-2-en-1-one chemical structure, C21H15BrO, CAS 5631-98-1
1-(2-Bromophenyl)-3-(4-phenylphenyl)prop-2-en-1-one
CAS 5631-98-1C21H15BrO
4-Phenylchalcone chemical structure, C21H16O, CAS 2403-28-3
4-Phenylchalcone
CAS 2403-28-3C21H16O
(Z)-4-Bromo-1-phenyl-3-(4-phenylphenyl)but-2-en-1-one chemical structure, C22H17BrO, CAS 27644-92-4
(Z)-4-Bromo-1-phenyl-3-(4-phenylphenyl)but-2-en-1-one
CAS 27644-92-4C22H17BrO
(2E)-1-(4-Fluorophenyl)-3-(4-phenylphenyl)prop-2-en-1-one chemical structure, C21H15FO, CAS 1002528-16-6
(2E)-1-(4-Fluorophenyl)-3-(4-phenylphenyl)prop-2-en-1-one
CAS 1002528-16-6C21H15FO
(2E)-1-(4-Aminophenyl)-3-biphenyl-4-YL-prop-2-EN-1-one chemical structure, C21H17NO, CAS 899588-25-1
(2E)-1-(4-Aminophenyl)-3-biphenyl-4-YL-prop-2-EN-1-one
CAS 899588-25-1C21H17NO
(2E)-1-(4-Aminophenyl)-3-biphenyl-4-ylprop-2-en-1-one chemical structure, C21H17NO
(2E)-1-(4-Aminophenyl)-3-biphenyl-4-ylprop-2-en-1-one
C21H17NO
(2E)-1-(2-Fluorophenyl)-3-(4-phenylphenyl)prop-2-en-1-one chemical structure, C21H15FO, CAS 1706522-39-5
(2E)-1-(2-Fluorophenyl)-3-(4-phenylphenyl)prop-2-en-1-one
CAS 1706522-39-5C21H15FO
(2E)-1-(2-Methoxyphenyl)-3-(4-phenylphenyl)prop-2-en-1-one chemical structure, C22H18O2, CAS 1373550-73-2
(2E)-1-(2-Methoxyphenyl)-3-(4-phenylphenyl)prop-2-en-1-one
CAS 1373550-73-2C22H18O2