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Murcko scaffold

1-Benzoyl-4-phenylpiperazine scaffold

844 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
844
With full pages
177
Scaffold SMILES

O=C(c1ccccc1)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzoyl-4-phenylpiperazine page
Murcko scaffold O=C(c1ccccc1)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 844 chemicals

[4-(2-Methoxyphenyl)piperazin-1-yl]-phenylmethanone chemical structure, C18H20N2O2, CAS 21057-12-5
[4-(2-Methoxyphenyl)piperazin-1-yl]-phenylmethanone
CAS 21057-12-5C18H20N2O2
4-(Dimethylamino)phenyl 4-(4-fluorophenyl)piperazinyl ketone chemical structure, C19H22FN3O, CAS 5666-42-2
4-(Dimethylamino)phenyl 4-(4-fluorophenyl)piperazinyl ketone
CAS 5666-42-2C19H22FN3O
(3,4-Dichlorophenyl)-(4-phenylpiperazin-1-yl)methanone chemical structure, C17H16Cl2N2O, CAS 33754-55-1
(3,4-Dichlorophenyl)-(4-phenylpiperazin-1-yl)methanone
CAS 33754-55-1C17H16Cl2N2O
[4-(2-Methoxyphenyl)piperazin-1-yl]-(2-methylphenyl)methanone chemical structure, C19H22N2O2, CAS 312594-11-9
[4-(2-Methoxyphenyl)piperazin-1-yl]-(2-methylphenyl)methanone
CAS 312594-11-9C19H22N2O2
1-(3-Chlorophenyl)-4-(4-fluorobenzoyl)piperazine chemical structure, C17H16ClFN2O, CAS 314284-54-3
1-(3-Chlorophenyl)-4-(4-fluorobenzoyl)piperazine
CAS 314284-54-3C17H16ClFN2O
4-(tert-Butyl)phenyl 4-phenylpiperazinyl ketone chemical structure, C21H26N2O, CAS 330216-79-0
4-(tert-Butyl)phenyl 4-phenylpiperazinyl ketone
CAS 330216-79-0C21H26N2O
(2,6-Dichlorophenyl)-(4-phenylpiperazin-1-yl)methanone chemical structure, C17H16Cl2N2O, CAS 329931-02-4
(2,6-Dichlorophenyl)-(4-phenylpiperazin-1-yl)methanone
CAS 329931-02-4C17H16Cl2N2O
[4-(4-Fluorophenyl)piperazin-1-yl]-(3-methyl-4-nitrophenyl)methanone chemical structure, C18H18FN3O3, CAS 329219-11-6
[4-(4-Fluorophenyl)piperazin-1-yl]-(3-methyl-4-nitrophenyl)methanone
CAS 329219-11-6C18H18FN3O3
(4-Chlorophenyl)[4-(3-chlorophenyl)piperazin-1-yl]methanone chemical structure, C17H16Cl2N2O, CAS 346724-06-9
(4-Chlorophenyl)[4-(3-chlorophenyl)piperazin-1-yl]methanone
CAS 346724-06-9C17H16Cl2N2O
N-[2-(4-Phenylpiperazine-1-carbonyl)phenyl]acetamide chemical structure, C19H21N3O2, CAS 309925-26-6
N-[2-(4-Phenylpiperazine-1-carbonyl)phenyl]acetamide
CAS 309925-26-6C19H21N3O2
N-[4-(4-Phenylpiperazine-1-carbonyl)phenyl]acetamide chemical structure, C19H21N3O2, CAS 349394-78-1
N-[4-(4-Phenylpiperazine-1-carbonyl)phenyl]acetamide
CAS 349394-78-1C19H21N3O2
1-(4-Nitrobenzoyl)-4-phenylpiperazine chemical structure, C17H17N3O3, CAS 21091-97-4
1-(4-Nitrobenzoyl)-4-phenylpiperazine
CAS 21091-97-4C17H17N3O3
(4-(2-Methoxyphenyl)piperazin-1-yl)(3-nitrophenyl)methanone chemical structure, C18H19N3O4, CAS 21092-01-3
(4-(2-Methoxyphenyl)piperazin-1-yl)(3-nitrophenyl)methanone
CAS 21092-01-3C18H19N3O4
4-(2-Methoxyphenyl)piperazinyl 4-nitrophenyl ketone chemical structure, C18H19N3O4, CAS 21091-99-6
4-(2-Methoxyphenyl)piperazinyl 4-nitrophenyl ketone
CAS 21091-99-6C18H19N3O4
1-(3-Chlorophenyl)-4-[(3-chlorophenyl)carbonyl]piperazine chemical structure, C17H16Cl2N2O, CAS 314284-61-2
1-(3-Chlorophenyl)-4-[(3-chlorophenyl)carbonyl]piperazine
CAS 314284-61-2C17H16Cl2N2O
(3-Methoxyphenyl)-[4-(2-methylphenyl)piperazin-1-yl]methanone chemical structure, C19H22N2O2, CAS 364628-89-7
(3-Methoxyphenyl)-[4-(2-methylphenyl)piperazin-1-yl]methanone
CAS 364628-89-7C19H22N2O2
2-(4-Phenylpiperazine-1-carbonyl)benzoic acid chemical structure, C18H18N2O3, CAS 72547-58-1
2-(4-Phenylpiperazine-1-carbonyl)benzoic acid
CAS 72547-58-1C18H18N2O3
1-(4-Ethoxybenzoyl)-4-phenylpiperazine chemical structure, C19H22N2O2, CAS 329938-09-2
1-(4-Ethoxybenzoyl)-4-phenylpiperazine
CAS 329938-09-2C19H22N2O2
Piperazine, 1-(4-methoxybenzoyl)-4-phenyl- chemical structure, C18H20N2O2, CAS 21091-90-7
Piperazine, 1-(4-methoxybenzoyl)-4-phenyl-
CAS 21091-90-7C18H20N2O2
1-(3-Chlorophenyl)-4-(3-nitrobenzoyl)piperazine chemical structure, C17H16ClN3O3, CAS 329939-30-2
1-(3-Chlorophenyl)-4-(3-nitrobenzoyl)piperazine
CAS 329939-30-2C17H16ClN3O3
1-(2-Chloro-5-nitrobenzoyl)-4-phenylpiperazine chemical structure, C17H16ClN3O3, CAS 329939-92-6
1-(2-Chloro-5-nitrobenzoyl)-4-phenylpiperazine
CAS 329939-92-6C17H16ClN3O3
(4-Methyl-3-nitrophenyl)-(4-phenylpiperazin-1-yl)methanone chemical structure, C18H19N3O3, CAS 329940-45-6
(4-Methyl-3-nitrophenyl)-(4-phenylpiperazin-1-yl)methanone
CAS 329940-45-6C18H19N3O3
(4-(2,4-Dimethylphenyl)piperazin-1-yl)(2-fluorophenyl)methanone chemical structure, C19H21FN2O, CAS 694515-07-6
(4-(2,4-Dimethylphenyl)piperazin-1-yl)(2-fluorophenyl)methanone
CAS 694515-07-6C19H21FN2O
1-(3-Methoxybenzoyl)-4-(2-methoxyphenyl)piperazine chemical structure, C19H22N2O3, CAS 260553-10-4
1-(3-Methoxybenzoyl)-4-(2-methoxyphenyl)piperazine
CAS 260553-10-4C19H22N2O3