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Murcko scaffold

1-Benzoyl-4-phenylpiperazine scaffold

844 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
844
With full pages
177
Scaffold SMILES

O=C(c1ccccc1)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzoyl-4-phenylpiperazine page
Murcko scaffold O=C(c1ccccc1)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 844 chemicals

1-(3-Chlorobenzoyl)-4-(2-methoxyphenyl)piperazine chemical structure, C18H19ClN2O2, CAS 303139-18-6
1-(3-Chlorobenzoyl)-4-(2-methoxyphenyl)piperazine
CAS 303139-18-6C18H19ClN2O2
(4-Fluorophenyl)[4-(2-methoxyphenyl)piperazin-1-yl]methanone chemical structure, C18H19FN2O2, CAS 326902-20-9
(4-Fluorophenyl)[4-(2-methoxyphenyl)piperazin-1-yl]methanone
CAS 326902-20-9C18H19FN2O2
(2-Ethoxyphenyl)-[4-(2-fluorophenyl)piperazin-1-yl]methanone chemical structure, C19H21FN2O2, CAS 432540-53-9
(2-Ethoxyphenyl)-[4-(2-fluorophenyl)piperazin-1-yl]methanone
CAS 432540-53-9C19H21FN2O2
1-(2-Methoxyphenyl)-4-(3-methylbenzoyl)piperazine chemical structure, C19H22N2O2, CAS 260442-75-9
1-(2-Methoxyphenyl)-4-(3-methylbenzoyl)piperazine
CAS 260442-75-9C19H22N2O2
1-{3-Nitro-2-methylbenzoyl}-4-phenylpiperazine chemical structure, C18H19N3O3, CAS 314284-31-6
1-{3-Nitro-2-methylbenzoyl}-4-phenylpiperazine
CAS 314284-31-6C18H19N3O3
1-(4-Bromobenzoyl)-4-phenylpiperazine chemical structure, C17H17BrN2O, CAS 339284-42-3
1-(4-Bromobenzoyl)-4-phenylpiperazine
CAS 339284-42-3C17H17BrN2O
[4-(4-Fluoro-phenyl)-piperazin-1-yl]-o-tolyl-methanone chemical structure, C18H19FN2O, CAS 5374-70-9
[4-(4-Fluoro-phenyl)-piperazin-1-yl]-o-tolyl-methanone
CAS 5374-70-9C18H19FN2O
(4-Chloro-3-nitrophenyl)(4-phenylpiperazin-1-yl)methanone chemical structure, C17H16ClN3O3, CAS 314284-36-1
(4-Chloro-3-nitrophenyl)(4-phenylpiperazin-1-yl)methanone
CAS 314284-36-1C17H16ClN3O3
[4-(4-Chlorophenyl)piperazin-1-yl]-(4-methylphenyl)methanone chemical structure, C18H19ClN2O, CAS 289631-81-8
[4-(4-Chlorophenyl)piperazin-1-yl]-(4-methylphenyl)methanone
CAS 289631-81-8C18H19ClN2O
1-(2,4-Dichlorobenzoyl)-4-(2-methylphenyl)piperazine chemical structure, C18H18Cl2N2O, CAS 853254-34-9
1-(2,4-Dichlorobenzoyl)-4-(2-methylphenyl)piperazine
CAS 853254-34-9C18H18Cl2N2O
N-[4-(4-Benzoylpiperazin-1-yl)phenyl]acetamide chemical structure, C19H21N3O2, CAS 428824-39-9
N-[4-(4-Benzoylpiperazin-1-yl)phenyl]acetamide
CAS 428824-39-9C19H21N3O2
1-(3-Fluorobenzoyl)-4-(2-methoxyphenyl)piperazine chemical structure, C18H19FN2O2, CAS 353770-17-9
1-(3-Fluorobenzoyl)-4-(2-methoxyphenyl)piperazine
CAS 353770-17-9C18H19FN2O2
(2-Chloro-4-nitrophenyl)-(4-phenylpiperazin-1-yl)methanone chemical structure, C17H16ClN3O3, CAS 349396-53-8
(2-Chloro-4-nitrophenyl)-(4-phenylpiperazin-1-yl)methanone
CAS 349396-53-8C17H16ClN3O3
[4-(4-Benzoylpiperazin-1-yl)phenyl]amine chemical structure, C17H19N3O, CAS 262375-99-5
[4-(4-Benzoylpiperazin-1-yl)phenyl]amine
CAS 262375-99-5C17H19N3O
4-(tert-Butyl)phenyl 4-(2-fluorophenyl)piperazinyl ketone chemical structure, C21H25FN2O, CAS 432015-75-3
4-(tert-Butyl)phenyl 4-(2-fluorophenyl)piperazinyl ketone
CAS 432015-75-3C21H25FN2O
1-{2-Nitrobenzoyl}-4-(2-methoxyphenyl)piperazine chemical structure, C18H19N3O4, CAS 331845-94-4
1-{2-Nitrobenzoyl}-4-(2-methoxyphenyl)piperazine
CAS 331845-94-4C18H19N3O4
[4-(3-Chlorophenyl)piperazin-1-yl]-(3,4-dimethylphenyl)methanone chemical structure, C19H21ClN2O, CAS 333348-15-5
[4-(3-Chlorophenyl)piperazin-1-yl]-(3,4-dimethylphenyl)methanone
CAS 333348-15-5C19H21ClN2O
(3,4-Dimethylphenyl)-[4-(2-methoxyphenyl)piperazin-1-yl]methanone chemical structure, C20H24N2O2, CAS 333348-18-8
(3,4-Dimethylphenyl)-[4-(2-methoxyphenyl)piperazin-1-yl]methanone
CAS 333348-18-8C20H24N2O2
(4-Ethoxyphenyl)-[4-(2-methoxyphenyl)piperazin-1-yl]methanone chemical structure, C20H24N2O3, CAS 333348-64-4
(4-Ethoxyphenyl)-[4-(2-methoxyphenyl)piperazin-1-yl]methanone
CAS 333348-64-4C20H24N2O3
(4-Chloro-2-nitrophenyl)-(4-phenylpiperazin-1-yl)methanone chemical structure, C17H16ClN3O3, CAS 333346-46-6
(4-Chloro-2-nitrophenyl)-(4-phenylpiperazin-1-yl)methanone
CAS 333346-46-6C17H16ClN3O3
(2-Methoxyphenyl)-(4-phenylpiperazin-1-yl)methanone chemical structure, C18H20N2O2, CAS 19351-49-6
(2-Methoxyphenyl)-(4-phenylpiperazin-1-yl)methanone
CAS 19351-49-6C18H20N2O2
(2-Chlorophenyl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone chemical structure, C18H19ClN2O2, CAS 21091-85-0
(2-Chlorophenyl)(4-(2-methoxyphenyl)piperazin-1-yl)methanone
CAS 21091-85-0C18H19ClN2O2
4-{[4-(2-Fluorophenyl)piperazin-1-yl]carbonyl}phenyl acetate chemical structure, C19H19FN2O3, CAS 433235-74-6
4-{[4-(2-Fluorophenyl)piperazin-1-yl]carbonyl}phenyl acetate
CAS 433235-74-6C19H19FN2O3
(2-Fluorophenyl)[4-(4-fluorophenyl)piperazin-1-yl]methanone chemical structure, C17H16F2N2O, CAS 5537-14-4
(2-Fluorophenyl)[4-(4-fluorophenyl)piperazin-1-yl]methanone
CAS 5537-14-4C17H16F2N2O