Browse by ring system
Murcko scaffolds
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: its rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
- Scaffolds with a page
- 15.8K
- Distinct scaffolds computed
- 545.2K
Scaffolds with the most chemicals
Each scaffold here is shared by at least 3 chemicals with full pages. Very common single rings such as benzene and pyridine are left out.
Showing 601 to 660 of 15,838 scaffolds
![Scaffold O=C(CNC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1cnc[nH]1)NC(=O)C1CCC(=O)N1)NCC(=O)N1CCCC1](/scaffold/XYWKFTDJACVKAX-UHFFFAOYSA-N/structure.svg)
O=C(CNC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1cnc[nH]1)NC(=O)C1CCC(=O)N1)NCC(=O)N1CCCC144 chemicals, 6 rings
2-(Benzylsulfanyl)-1,3,4-thiadiazole44 chemicals, 2 rings
3-Azabicyclo(3.2.1)octane43 chemicals, 2 rings
N-Benzyl-2-phenylacetamide43 chemicals, 2 rings
N-Phenylisonicotinamide43 chemicals, 2 rings
N-Phenylcyclopentanecarboxamide43 chemicals, 2 rings
4H-1,4-Benzothiazin-3-one43 chemicals, 2 rings
5-Azaspiro(2.4)heptane43 chemicals, 2 rings
3-Benzyl-2H-1-benzopyran-2-one43 chemicals, 3 rings
1-Cyclopentyl-1H-pyrazole43 chemicals, 2 rings
O=c1oc2ccccc2c2c1CCCC243 chemicals, 3 rings
Phthalic anhydride43 chemicals, 2 rings
O=C(C=Cc1ccccc1)NCc1ccccc143 chemicals, 2 rings
O=c1ccn(C2CC2)c2cc(N3CCNCC3)ccc1243 chemicals, 4 rings
N-Phenylquinolin-4-amine43 chemicals, 3 rings
Dibenzoylmethane43 chemicals, 2 rings![Scaffold O=c1[nH]cnc2[nH]ncc12](/scaffold/OFCNXPDARWKPPY-UHFFFAOYSA-N/structure.svg)
Allopurinol43 chemicals, 2 rings
2-Phenoxy-N-(1,3-thiazol-2-yl)acetamide43 chemicals, 2 rings
1,3-Dihydroisobenzofuran43 chemicals, 2 rings
1-(Benzenesulfonyl)azepane43 chemicals, 2 rings![Scaffold N=c1[nH]c2ccccc2s1](/scaffold/UHGULLIUJBCTEF-UHFFFAOYSA-N/structure.svg)
Benzo(d)thiazol-2-amine43 chemicals, 2 rings![Scaffold O=c1[nH]ncn1-c1ccccc1](/scaffold/UYVVGXZLFHZTKT-UHFFFAOYSA-N/structure.svg)
4-Phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one43 chemicals, 2 rings
1-(Phenylsulfonyl)-1H-indole43 chemicals, 3 rings
4-Phenylquinazoline43 chemicals, 3 rings![Scaffold c1n[nH]c2c1CNCC2](/scaffold/VGMJQHONPAXABH-UHFFFAOYSA-N/structure.svg)
4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine43 chemicals, 2 rings
1,5-Naphthyridine43 chemicals, 2 rings
1,6-Naphthyridine43 chemicals, 2 rings
O=C(NN=Cc1c(OC(=O)c2ccccc2)ccc2ccccc12)C(=O)Nc1ccccc143 chemicals, 4 rings
1-Phenyladamantane43 chemicals, 5 rings
RefChem:35720443 chemicals, 3 rings![Scaffold O=c1cc[nH]c(=S)[nH]1](/scaffold/ZEMGGZBWXRYJHK-UHFFFAOYSA-N/structure.svg)
Thiouracil43 chemicals, 1 ring![Scaffold O=c1cccc(-c2ccccc2)[nH]1](/scaffold/ZLUIDXRFWSPPCC-UHFFFAOYSA-N/structure.svg)
6-Phenyl-2-pyridone43 chemicals, 2 rings
O=C1C=C(C2CCC3C2CCC2C4CCC(OC5CCCCO5)CC4CCC23)CO142 chemicals, 6 rings
Benzene, ((phenylmethyl)sulfonyl)-42 chemicals, 2 rings
Pyrazinecarboxanilide42 chemicals, 2 rings
2-(Benzyloxy)pyridine42 chemicals, 2 rings
4H,5H,6H,7H-Pyrazolo(1,5-a)pyrimidine42 chemicals, 2 rings
1,3,4,5-Tetrahydro-2H-1-benzazepin-2-one42 chemicals, 2 rings
Benzyl phenethylcarbamate42 chemicals, 2 rings
N-(1,3-Benzothiazol-2-yl)furan-2-carboxamide42 chemicals, 3 rings![Scaffold c1cc(B2OCCO2)n[nH]1](/scaffold/INSYJPNIRNOISO-UHFFFAOYSA-N/structure.svg)
c1cc(B2OCCO2)n[nH]142 chemicals, 2 rings
1-Phenyl-1,3-diazinane-2,4-dione42 chemicals, 2 rings
O=C(CSc1nnc(SCc2ccccc2)s1)Nc1ccccc142 chemicals, 3 rings
2-Phenylthiazolidine42 chemicals, 2 rings
3-Phenyl-1,2,4-thiadiazole42 chemicals, 2 rings
Quinolin-8-yl phenylcarbamate42 chemicals, 3 rings
Isoxazole, 4,5-dihydro-3-phenyl-42 chemicals, 2 rings![Scaffold O=c1[nH]c2ccccc2nc1-c1ccccc1](/scaffold/ZBBQSGVRBQKLLE-UHFFFAOYSA-N/structure.svg)
3-Phenylquinoxalin-2(1H)-one42 chemicals, 3 rings
Cyclohexene oxide42 chemicals, 2 rings
3-Benzylazetidine41 chemicals, 2 rings(c2ccccc2)c2ccccc2)cc1](/scaffold/BNQRPLGZFADFGA-UHFFFAOYSA-N/structure.svg)
Triphenyl(phenylmethyl)phosphonium41 chemicals, 4 rings
7-Azaspiro(3.5)nonane41 chemicals, 2 rings
N-Phenyl-1,3-benzodioxole-5-carboxamide41 chemicals, 3 rings
Benzisothiazole41 chemicals, 2 rings
Benzo[a]pyrene41 chemicals, 5 rings
O=c1cc(CN2CCCCC2)c2ccccc2o141 chemicals, 3 rings
Indolizine41 chemicals, 2 rings
1,3-Diphenoxypropane41 chemicals, 2 rings![Scaffold c1ccc2c(c1)-c1nc-2nc2[nH]c(nc3nc(nc4[nH]c(n1)c1ccccc41)-c1ccccc1-3)c1ccccc21](/scaffold/IEQIEDJGQAUEQZ-UHFFFAOYSA-N/structure.svg)
Phthalocyanine41 chemicals, 9 rings
Glutarimide41 chemicals, 1 ring