Browse by ring system
Murcko scaffolds
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: its rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
- Scaffolds with a page
- 15.8K
- Distinct scaffolds computed
- 545.2K
Scaffolds with the most chemicals
Each scaffold here is shared by at least 3 chemicals with full pages. Very common single rings such as benzene and pyridine are left out.
Showing 901 to 960 of 15,838 scaffolds
O=C1CCC2C1CCC1C3CCCCC3CCC2132 chemicals, 4 rings
N-Phenethyl-2-phenylacetamide32 chemicals, 2 rings
O=C(Nc1nc2ccccc2s1)C1CC132 chemicals, 3 rings
Cinnoline32 chemicals, 2 rings
3,4-Diphenyl-4H-1,2,4-triazole32 chemicals, 3 rings
2-Azabicyclo[3.1.0]hexane32 chemicals, 2 rings
O=C(c1ccccc1)N(Cc1ccccc1)C1CCS(=O)(=O)C132 chemicals, 3 rings![Scaffold O=c1cc(Nc2ccccc2)[nH]c(=O)[nH]1](/scaffold/XKWQUTFERHHKNT-UHFFFAOYSA-N/structure.svg)
6-Anilinouracil32 chemicals, 2 rings
Indene32 chemicals, 2 rings
Thioxanthone32 chemicals, 3 rings
[1,2,4]Triazolo[1,5-a]pyrimidine, 1,7-dihydro-5,7-diphenyl-32 chemicals, 4 rings
O=C(COc1ccccc1)NN=CC=Cc1ccccc131 chemicals, 2 rings
3-Phenoxyazetidine31 chemicals, 2 rings
1H-Indol-1-ylphenylmethanone31 chemicals, 3 rings
6-Phenylimidazo[2,1-b]thiazole31 chemicals, 3 rings
2,5-Pyrrolidinedione, 1-phenyl-3-(phenylthio)-31 chemicals, 3 rings
c1ccc(C(Nc2ccccn2)c2ccc3cccnc3c2)cc131 chemicals, 4 rings
O=C1C=CC(c2ccccc2)N131 chemicals, 2 rings
Indolizidine31 chemicals, 2 rings
c1ccc2cc(N=Nc3ccc(-c4ccc(N=Nc5ccc6ccccc6c5)cc4)cc3)ccc2c131 chemicals, 6 rings
2-Benzylpiperidine31 chemicals, 2 rings
2-Propen-1-one, 1-phenyl-3-(phenylamino)-31 chemicals, 2 rings
2-Phenyloxazolo[4,5-b]pyridine31 chemicals, 3 rings
Tetrahydro-2-((tetrahydro-2-furanyl)oxy)-2H-pyran31 chemicals, 2 rings
O=C(Cc1ccccc1)NC1C(=O)N2C=CCSC1231 chemicals, 3 rings![Scaffold O=c1[nH]cnc2sc3c(c12)CCC3](/scaffold/MZAZSAHKQBGEMA-UHFFFAOYSA-N/structure.svg)
1,5,6,7-Tetrahydro-4H-cyclopenta(4,5)thieno(2,3-d)pyrimidin-4-one31 chemicals, 3 rings
N-(4-Phenyl-thiazol-2-yl)-benzamide31 chemicals, 3 rings
n-Benzyl-n-phenylbenzenesulfonamide31 chemicals, 3 rings
2-(Diphenylmethyl)pyrrolidine31 chemicals, 3 rings
C(=Nc1ncccn1)Nc1ccccc131 chemicals, 2 rings
1-Phenylsulfonylpyrrole31 chemicals, 2 rings![Scaffold O=c1cc(-c2ccccc2)c2ccccc2[nH]1](/scaffold/QKQNVNSIRYIHDD-UHFFFAOYSA-N/structure.svg)
3-Deoxyviridicatin31 chemicals, 3 rings
N-Benzylthiazol-2-amine31 chemicals, 2 rings
O=C(CNCc1ccccc1)Nc1ccccc131 chemicals, 2 rings
O=C(NC=Cc1ccccc1)c1ccccc131 chemicals, 2 rings
O=C(CSc1nnc(CSc2ccccc2)n1-c1ccccc1)Nc1ccccc131 chemicals, 4 rings
Cubane31 chemicals, 6 rings![Scaffold O=C(CSc1nncc(=O)[nH]1)Nc1ccccc1](/scaffold/UYFAYUUIFGQXHQ-UHFFFAOYSA-N/structure.svg)
2-((5-Oxo-4,5-dihydro-1,2,4-triazin-3-yl)thio)-N-phenylacetamide31 chemicals, 2 rings
N-(2-Morpholinoethyl)benzamide31 chemicals, 2 rings
N-Phenyl-1-piperidineacetamide31 chemicals, 2 rings![Scaffold S=c1[nH]nc(COc2ccccc2)n1N=Cc1ccccc1](/scaffold/WIMFCFWDUQGEKM-UHFFFAOYSA-N/structure.svg)
S=c1[nH]nc(COc2ccccc2)n1N=Cc1ccccc131 chemicals, 3 rings
O=C(C=Cc1ccccc1)C=Cc1ccccc131 chemicals, 2 rings
Bicyclohexyl31 chemicals, 2 rings
3-Anilino-1-phenylsuccinimide31 chemicals, 3 rings
C(=NN1CCN(c2ccccc2)CC1)c1ccccc131 chemicals, 3 rings
Furo(3,2-b)pyridine31 chemicals, 2 rings
c1ccc(CSc2nnc(-c3ccncc3)n2-c2ccccc2)cc130 chemicals, 4 rings
1-Cyclobutyl-1H-pyrazole30 chemicals, 2 rings
2-Benzylsulfanylpyrimidine30 chemicals, 2 rings
5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine30 chemicals, 3 rings
N-Phenylpyridin-4-amine30 chemicals, 2 rings![Scaffold O=c1[nH]c(=O)c2c(ncn2Cc2cccc3ccccc23)[nH]1](/scaffold/DYOXONGUUVOGFO-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2c(ncn2Cc2cccc3ccccc23)[nH]130 chemicals, 4 rings
Thieno(2,3-c)pyridine30 chemicals, 2 rings
O=c1ccoc(CN2CCN(c3ccccc3)CC2)c130 chemicals, 3 rings
Spiro(2.4)heptane30 chemicals, 2 rings
1,2-Dihydroquinoline30 chemicals, 2 rings
N-2-Picolylbenzamide30 chemicals, 2 rings
1-Phenyl-3-[(2-phenylethyl)amino]-2,5-pyrrolidinedione30 chemicals, 3 rings
4-Phenylisoxazole30 chemicals, 2 rings![Scaffold O=C(CSc1nc2c(c(=O)[nH]1)SCC2)Nc1ccccc1](/scaffold/KWKBTUZTPFTONF-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nc2c(c(=O)[nH]1)SCC2)Nc1ccccc130 chemicals, 3 rings