Browse by ring system
Murcko scaffolds
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: its rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
- Scaffolds with a page
- 15.8K
- Distinct scaffolds computed
- 545.2K
Scaffolds with the most chemicals
Each scaffold here is shared by at least 3 chemicals with full pages. Very common single rings such as benzene and pyridine are left out.
Showing 841 to 900 of 15,838 scaffolds
Thiazolo(5,4-b)pyridine34 chemicals, 2 rings
Piperazine, 1-(3-phenoxypropyl)-4-phenyl-34 chemicals, 3 rings![Scaffold O=c1cc[nH]c2cc(N3CCNCC3)ccc12](/scaffold/AFBYMUXIPJIETH-UHFFFAOYSA-N/structure.svg)
O=c1cc[nH]c2cc(N3CCNCC3)ccc1233 chemicals, 3 rings
1-(Phenylsulfonyl)indoline33 chemicals, 3 rings
4-Phenyl-1,2,3-thiadiazole33 chemicals, 2 rings
7H-Furo[3,2-g][1]benzopyran-7-one, 3-phenyl-33 chemicals, 4 rings
2-(Benzylthio)-N-phenylacetamide33 chemicals, 2 rings
O=C(CN1CCNCC1)Nc1ccccc133 chemicals, 2 rings
N-(2H-1,3-Benzodioxol-5-yl)benzamide33 chemicals, 3 rings![Scaffold S=c1[nH]nc(-c2ccccc2)o1](/scaffold/FOHWXVBZGSVUGO-UHFFFAOYSA-N/structure.svg)
5-Phenyl-1,3,4-oxadiazole-2-thiol33 chemicals, 2 rings
1,2,3,4,4a,5,6,8a-Octahydro-naphthalene33 chemicals, 2 rings
O=C(NN=Cc1cccc(OC(=O)c2ccccc2)c1)c1ccccc133 chemicals, 3 rings
(4-Benzenesulfonyl-piperazin-1-yl)-furan-2-yl-methanone33 chemicals, 3 rings![Scaffold c1ccc(Cc2cnc[nH]2)cc1](/scaffold/HREUGOAZLRNTEM-UHFFFAOYSA-N/structure.svg)
4-Benzyl-1H-imidazole33 chemicals, 2 rings
Dibenzothiophene33 chemicals, 3 rings
O=C(c1ccccc1)N1CCc2ccccc2133 chemicals, 3 rings
4-Phenoxypyridine33 chemicals, 2 rings
2-Benzylsulfanyl-3-phenyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one33 chemicals, 5 rings
3-Azabicyclo(3.1.1)heptane33 chemicals, 3 rings
3-Phenoxypyrrolidine33 chemicals, 2 rings
2-Oxabicyclo[3.1.1]heptane33 chemicals, 3 rings
9,10-Ethanoanthracene, 9,10-dihydro-33 chemicals, 5 rings
cis,cis-1,5-Cyclooctadiene33 chemicals, 1 ring
4-(1H-Pyrazol-1-yl)piperidine33 chemicals, 2 rings
N-Phenyl-2-[(phenylsulfonyl)anilino]acetamide33 chemicals, 3 rings
O=C1CCC2OC2CC2CC(CC=CC=CCc3cccc(c3)N1)NC(=O)O233 chemicals, 4 rings
1H-Pyrazole, 4,5-dihydro-3-phenyl-5-(thienyl)-33 chemicals, 3 rings
Triphenyl phosphate33 chemicals, 3 rings
c1cc(N2CCCCC2)ncn133 chemicals, 2 rings
M-Terphenyl33 chemicals, 3 rings
O=S(=O)(NN=Cc1ccccc1)c1ccccc133 chemicals, 2 rings
N,N'-Diphenylformamidine33 chemicals, 2 rings![Scaffold N=c1[nH]c2nc3ccccn3c(=O)c2cc1C(=O)NCc1ccccc1](/scaffold/AGNSTMFRCXFPBS-UHFFFAOYSA-N/structure.svg)
N=c1[nH]c2nc3ccccn3c(=O)c2cc1C(=O)NCc1ccccc132 chemicals, 4 rings
3-(5-(Benzylthio)-4-phenyl-4H-1,2,4-triazol-3-yl)pyridine32 chemicals, 4 rings
N-(1,3,4-Thiadiazol-2-yl)benzenesulfonamide32 chemicals, 2 rings
2,3-Dihydro-2-phenyl-1H-isoindol-1-one32 chemicals, 3 rings
5-Azaspiro[3.4]octane32 chemicals, 2 rings
1-(Phenylsulfonyl)-1,2,3,4-tetrahydroquinoline32 chemicals, 3 rings![Scaffold O=c1[nH]c(=O)c2[nH]c(NCc3ccccc3)nc2[nH]1](/scaffold/GWEJMPIBANKNEQ-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]c(NCc3ccccc3)nc2[nH]132 chemicals, 3 rings
c1ccc(-n2cc3c(n2)CSC3)cc132 chemicals, 3 rings
5H,6H,7H-Pyrazolo[3,2-b][1,3]oxazine32 chemicals, 2 rings
1-Phenylnaphthalene32 chemicals, 3 rings
2,2-Diphenylacetanilide32 chemicals, 3 rings![Scaffold O=c1[nH]c(C=Cc2ccccc2)nc2ccccc12](/scaffold/JDEJRLXMWUYMSS-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(C=Cc2ccccc2)nc2ccccc1232 chemicals, 3 rings
2-(Dicyclohexylphosphino)biphenyl32 chemicals, 4 rings
2-Piperazin-1-yl-1,3-benzothiazole32 chemicals, 3 rings
O=C(Nc1ccccc1)C1CCCCN132 chemicals, 2 rings
2-(1H-Imidazol-1-yl)pyridine32 chemicals, 2 rings
1,7-Naphthyridine32 chemicals, 2 rings![Scaffold c1ccc(Cc2ncc[nH]2)cc1](/scaffold/NAPDOWNULRULLI-UHFFFAOYSA-N/structure.svg)
2-Benzyl-1H-imidazole32 chemicals, 2 rings
Isoflavan32 chemicals, 3 rings
4-Phenyl-4H-1-benzopyran32 chemicals, 3 rings
2-Phenylamino-1,4-naphthoquinone32 chemicals, 3 rings
1-Phenylazetidin-2-one32 chemicals, 2 rings
1-Phenyl-4-(pyridin-2-yl)piperazine32 chemicals, 3 rings
4-Cyclopropyl-1,3-thiazole32 chemicals, 2 rings
c1ccc(-n2ncc3c2CCC3)cc132 chemicals, 3 rings
1-Phenylimidazolidin-2-one32 chemicals, 2 rings
2,3-Dihydro-3-phenyl-4H-1-benzopyran-4-one32 chemicals, 3 rings![Scaffold O=c1ccc(-c2ccccc2)c[nH]1](/scaffold/RWFAQYWIBBVEBY-UHFFFAOYSA-N/structure.svg)
2-Hydroxy-5-phenylpyridine32 chemicals, 2 rings