Browse by ring system
Murcko scaffolds
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: its rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
- Scaffolds with a page
- 15.8K
- Distinct scaffolds computed
- 545.2K
Scaffolds with the most chemicals
Each scaffold here is shared by at least 3 chemicals with full pages. Very common single rings such as benzene and pyridine are left out.
Showing 1,261 to 1,320 of 15,838 scaffolds
1,4,7,10-Tetraazacyclododecane24 chemicals, 1 ring
1,4'-Bipiperidine24 chemicals, 2 rings
O=c1c(OC2CCCC(COC3CCCCO3)O2)c(-c2ccccc2)oc2ccccc1224 chemicals, 5 rings
N-(1,2,4)Triazol-4-YL-benzamide24 chemicals, 2 rings![Scaffold O=c1[nH]c(=O)c2c(nc3n2CCCN3CCc2ccccc2)[nH]1](/scaffold/QLOLLCKBSPFJHV-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2c(nc3n2CCCN3CCc2ccccc2)[nH]124 chemicals, 4 rings
O=C1CC2OCC=C3CN4CCC56c7ccccc7N1C5C2C3CC4624 chemicals, 7 rings
Oxazolo(4,5-b)pyridine24 chemicals, 2 rings
Pyrrolo(1,2-a)pyrazine24 chemicals, 2 rings
9-Iminofluorene24 chemicals, 3 rings
Tropone24 chemicals, 1 ring
C1=CC2c3ccccc3OCC2CC124 chemicals, 3 rings
1-Furfuryl-3-phenyl-2-thiourea24 chemicals, 2 rings
2-Benzylisoindolin-1-one24 chemicals, 3 rings
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(furan-2-ylmethyl)benzamide24 chemicals, 3 rings
1,3,5-Triphenylbenzene24 chemicals, 4 rings
2-Pyrrolidinone, 5-phenyl-24 chemicals, 2 rings
N-Phenylpyrimidine-4-carboxamide24 chemicals, 2 rings
1,3-Indandione24 chemicals, 2 rings
N-Phenyl-3-(4-phenylpiperazin-1-yl)propanamide24 chemicals, 3 rings
4-Benzoyl-1,2,3,4-tetrahydroquinoxalin-2-one24 chemicals, 3 rings
1-Phenyl-3-(pyridin-2-ylmethyl)urea24 chemicals, 2 rings
2-Phenyl-N-(1,3,4-thiadiazol-2-yl)acetamide24 chemicals, 2 rings![Scaffold c1ccc(Cc2ncn[nH]2)cc1](/scaffold/VZEAUAKJULSHNO-UHFFFAOYSA-N/structure.svg)
3-Benzyl-4H-1,2,4-triazole24 chemicals, 2 rings
C1CC2CCOC3OC4CCC(C1)C23OO424 chemicals, 5 rings
1-(Phenylsulfonyl)-4-(2-pyridinyl)piperazine24 chemicals, 3 rings
4-Cyclopropylpyridine24 chemicals, 2 rings
O=C1C=C2C3CCCC3CCC2C2CCCCC1224 chemicals, 4 rings
2-Indolinone, 3-(phenylimino)-24 chemicals, 3 rings
O=C(COC(=O)c1ccccc1)Nc1ccccc124 chemicals, 2 rings![Scaffold O=C(OCc1ccccc1)c1ccc[nH]1](/scaffold/XTKILPAAGBOZHY-UHFFFAOYSA-N/structure.svg)
Benzyl 1H-pyrrole-2-carboxylate24 chemicals, 2 rings
4-(3-Phenoxypropyl)morpholine24 chemicals, 2 rings
9,10-Dihydrophenanthrene24 chemicals, 3 rings
2,4-Diphenylpyridine24 chemicals, 3 rings
N-Phenylpiperazine-1-carboxamide24 chemicals, 2 rings
O=C(NN=Cc1ccc(OC(=O)c2ccccc2)cc1)c1ccc(OCc2ccccc2)cc124 chemicals, 4 rings![Scaffold O=C(NCCc1nc2ccccc2[nH]1)c1ccccc1](/scaffold/YRGGTYXDASSWSH-UHFFFAOYSA-N/structure.svg)
N-[2-(1H-Benzoimidazol-2-yl)-ethyl]-benzamide24 chemicals, 3 rings
1H,2H,3H-Pyrrolo(2,3-b)pyridine24 chemicals, 2 ringsc2ccccc2)cc1](/scaffold/AKQNYQDSIDKVJZ-UHFFFAOYSA-N/structure.svg)
Triphenylsilane23 chemicals, 3 rings
N-Phenyl-2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetamide23 chemicals, 3 rings
Tricyclo(2.2.1.02,6)heptane23 chemicals, 4 rings
2-Phenyloxetane23 chemicals, 2 rings![Scaffold c1n[nH]c2c1CNC2](/scaffold/CVRWHBCQJCUBFE-UHFFFAOYSA-N/structure.svg)
1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole23 chemicals, 2 rings
Isoxazolo[5,4-B]pyridine23 chemicals, 2 rings
4-(2-Pyrimidinyl)morpholine23 chemicals, 2 rings
1H-Pyrazole, 4,5-dihydro-1,3,5-triphenyl-23 chemicals, 4 rings
5,6,7,8-Tetrahydro-1,6-naphthyridine23 chemicals, 2 rings
O=C(CCOc1ccccc1)Nc1ccccc123 chemicals, 2 rings
Deschloro ticlopidine23 chemicals, 3 rings
N-[(Furan-2-yl)methyl]aniline23 chemicals, 2 rings
5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-2(1H)-one23 chemicals, 3 rings
2-(1H-1,3-Benzodiazol-1-yl)-N-phenylacetamide23 chemicals, 3 rings
N-Phenyl-2-pyridone23 chemicals, 2 rings
C1COB(C2CC2)O123 chemicals, 2 rings
N-(1,1-Dioxidotetrahydrothiophen-3-yl)-2-phenoxy-N-(thiophen-2-ylmethyl)acetamide23 chemicals, 3 rings
c1ccc(CC2CCOCC2)cc123 chemicals, 2 rings![Scaffold c1ccc(COc2ccc3[nH]ccc3c2)cc1](/scaffold/JCQLPDZCNSVBMS-UHFFFAOYSA-N/structure.svg)
5-Benzyloxyindole23 chemicals, 3 rings
N-Phenyl-2-naphthylamine23 chemicals, 3 rings
1-(2-Phenylethyl)pyrrolidine23 chemicals, 2 rings
Benzosuberone23 chemicals, 2 rings
1-(Morpholin-4-yl)-2-phenoxyethan-1-one23 chemicals, 2 rings