Browse by ring system
Murcko scaffolds
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: its rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
- Scaffolds with a page
- 15.8K
- Distinct scaffolds computed
- 545.2K
Scaffolds with the most chemicals
Each scaffold here is shared by at least 3 chemicals with full pages. Very common single rings such as benzene and pyridine are left out.
Showing 1,321 to 1,380 of 15,838 scaffolds
N-(1,1-Dioxo-3-thiolanyl)-N-(thiophen-2-ylmethyl)benzamide23 chemicals, 3 rings
N=C(C(=O)NC1C(=O)N2C=CCSC12)c1cscn123 chemicals, 3 rings
O=C1C=C2C=CC3C4CCCC4CCC3C2CC123 chemicals, 4 rings
O=S(=O)(NCc1ccncc1)c1ccccc123 chemicals, 2 rings
O=c1c(-c2ccccc2)coc2cc(OC3CCCCO3)ccc1223 chemicals, 4 rings
N-(1,1-Dioxidotetrahydrothiophen-3-yl)benzamide23 chemicals, 2 rings
c1ccc(-c2cnn3c(N4CCOCC4)ccnc23)cc123 chemicals, 4 rings
N-Benzylidenebenzenesulfonamide23 chemicals, 2 rings
2-Phenylpyrazolo[1,5-a]pyrimidine23 chemicals, 3 rings![Scaffold c1ccc(-c2ccc3ccccc3[o+]2)cc1](/scaffold/NWKFECICNXDNOQ-UHFFFAOYSA-N/structure.svg)
Anthocyanins23 chemicals, 3 rings
O=C(Nc1cccc(-c2nc3ncccc3o2)c1)c1ccccc123 chemicals, 4 rings
Octahydroisoindole23 chemicals, 2 rings
O=C(COC(=O)c1cccnc1)c1ccccc123 chemicals, 2 rings
O=C(Nc1cc2c(s1)CCC2)c1ccccc123 chemicals, 3 rings
Anilinobenzothiazole23 chemicals, 3 rings
1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-phenyl-23 chemicals, 3 rings
N-Benzylpyrimidin-4-amine23 chemicals, 2 rings
4-(Oxolane-2-carbonyl)-N-phenylpiperazine-1-carbothioamide23 chemicals, 3 rings
N-Phenylcarbamoyl-1,2,3,4-tetrahydroisoquinoline23 chemicals, 3 rings
C1=C2C(=CCC3CCCCC23)C2CCCC2C123 chemicals, 4 rings
Phenyl morpholine-4-carboxylate23 chemicals, 2 rings
O=C1Nc2ccccc2C1=Cc1ccccc123 chemicals, 3 rings
N-Phenyl-2-((6-(pyridin-3-yl)pyridazin-3-yl)thio)acetamide23 chemicals, 3 rings
N-(1,3-Benzothiazol-2-yl)naphthalene-2-carboxamide23 chemicals, 4 rings
C1=CCCCCCC123 chemicals, 1 ring![Scaffold S=c1[nH]ccn1-c1ccccc1](/scaffold/VXEUGLRMYAXWKM-UHFFFAOYSA-N/structure.svg)
1-Phenyl-1H-imidazole-2-thiol23 chemicals, 2 ringsc2ccccc2)cc1](/scaffold/WLOQLWBIJZDHET-UHFFFAOYSA-N/structure.svg)
Triphenylsulfonium23 chemicals, 3 rings
c1ccc(NCc2cnc3ncncc3n2)cc123 chemicals, 3 rings
Dicyclohexylmethane23 chemicals, 2 rings
5-(Benzylsulfanyl)-1-phenyl-1H-1,2,3,4-tetrazole23 chemicals, 3 rings![Scaffold O=c1[nH]c(=O)c2[nH]c(CN3CCN(c4ccccc4)CC3)nc2[nH]1](/scaffold/YTMPIYKOADWLHU-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]c(CN3CCN(c4ccccc4)CC3)nc2[nH]123 chemicals, 4 rings
c1csc(-c2cscn2)c123 chemicals, 2 rings
O=C(C1=CC(=O)N(Cc2cccnc2)C1c1ccccc1)c1ccco123 chemicals, 4 rings![Scaffold O=c1[nH]c(=O)c2[nH]c(CN3CCCCC3)nc2[nH]1](/scaffold/ZFBIZJMWQYQTOH-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]c(CN3CCCCC3)nc2[nH]123 chemicals, 3 rings
1-Benzoyl-3-phenylurea23 chemicals, 2 rings![Scaffold O=c1[nH]ccn1-c1ccccc1](/scaffold/ZZNMRBGELWVJND-UHFFFAOYSA-N/structure.svg)
1-Phenyl-2,3-dihydro-1H-imidazol-2-one23 chemicals, 2 rings
Octahydrocyclopenta[B]pyrrole22 chemicals, 2 rings
N-(1,3-Benzothiazol-2-yl)-2-phenoxyacetamide22 chemicals, 3 rings
O=C(NN=Cc1ccccc1)c1cccnc122 chemicals, 2 rings
c1ccc(Cc2nncs2)cc122 chemicals, 2 rings![Scaffold C1=C(c2c[nH]c3ccccc23)CCNC1](/scaffold/CIRSPTXGPFAXRE-UHFFFAOYSA-N/structure.svg)
3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole22 chemicals, 3 rings
C1=CC2c3ccccc3NCC2C122 chemicals, 3 rings
5-Benzylidenebarbituric acid22 chemicals, 2 rings
3-Phenyl-tetrahydrofuran22 chemicals, 2 rings![Scaffold S=c1[nH]nc(COc2ccccc2)n1-c1ccccc1](/scaffold/CQOIKLYYYATDDP-UHFFFAOYSA-N/structure.svg)
2,4-Dihydro-5-(phenoxymethyl)-4-phenyl-3H-1,2,4-triazole-3-thione22 chemicals, 3 rings
O=C(NCCCn1ccnc1)c1ccccc122 chemicals, 2 rings
5-Anilino-1,3-thiazolidine-2,4-dione22 chemicals, 2 rings
C1CC2(CCO1)CC222 chemicals, 2 rings![Scaffold O=C(CSc1nnn[nH]1)Nc1ccccc1](/scaffold/FDRBWKCIVMSABC-UHFFFAOYSA-N/structure.svg)
O=C(CSc1nnn[nH]1)Nc1ccccc122 chemicals, 2 rings
N-Benzyl-3-phenylpropanamide22 chemicals, 2 rings
c1ccc(C2CC(c3cccs3)=NN2)cc122 chemicals, 3 rings
N-Phenylpyrrolidine-1-carbothioamide22 chemicals, 2 rings
1-(2-Phenylethyl)-1H-benzimidazole22 chemicals, 3 rings
3-(Benzenesulfonyl)-N-(1,3-benzothiazol-2-yl)propanamide22 chemicals, 3 rings
2,5-Bis(benzylsulfanyl)-1,3,4-thiadiazole22 chemicals, 3 rings![Scaffold O=c1[nH]cnc2c1NC(CNc1ccccc1)CN2](/scaffold/HSISPQXNAMHQIC-UHFFFAOYSA-N/structure.svg)
O=c1[nH]cnc2c1NC(CNc1ccccc1)CN222 chemicals, 3 rings
N-Phenyl-1,8-naphthalimide22 chemicals, 4 rings
N-Phenethyl-nicotinamide22 chemicals, 2 rings
c1coc(Cn2cccn2)c122 chemicals, 2 rings
N-Phenylazetidine22 chemicals, 2 rings