Browse by ring system
Murcko scaffolds
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: its rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
- Scaffolds with a page
- 15.8K
- Distinct scaffolds computed
- 545.2K
Scaffolds with the most chemicals
Each scaffold here is shared by at least 3 chemicals with full pages. Very common single rings such as benzene and pyridine are left out.
Showing 1,921 to 1,980 of 15,838 scaffolds
O=S1(=O)CCCc2ccccc2117 chemicals, 2 rings
2-Phenoxy-N-(tetrahydro-2-furanylmethyl)acetamide17 chemicals, 2 rings
O=c1ccn2c3c(c(N4CCNCC4)ccc13)OCC217 chemicals, 4 rings
C1=NC(c2ccccc2)n2c(nc3ccccc32)N117 chemicals, 4 rings
O=C(COc1ccccc1)N1CCOc2ccccc2117 chemicals, 3 rings
N-(5,5-Dioxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)benzamide17 chemicals, 4 rings
N-Phenylbenzenebutanamide17 chemicals, 2 rings![Scaffold c1ncc(C[n+]2ccsc2)cn1](/scaffold/VOZNMBMJVMRVOB-UHFFFAOYSA-N/structure.svg)
c1ncc(C[n+]2ccsc2)cn117 chemicals, 2 rings
O=C(Nc1ccccc1)Nc1nnc(Cc2ccccc2)s117 chemicals, 3 rings
1,2-Benzoquinone17 chemicals, 1 ring
c1ccc(-c2csc(Nc3ccccn3)n2)cc117 chemicals, 3 rings
O=c1nc2sc(=Cc3ccccc3)c(=O)n2nc1-c1ccccc117 chemicals, 4 rings
Ethylene dibenzoate17 chemicals, 2 rings![Scaffold O=c1[nH]cnc2sc3c(c12)CCOC3](/scaffold/YGTOWESQZGWBAZ-UHFFFAOYSA-N/structure.svg)
5,6-Dihydro-3H-pyrano[4',3':4,5]thieno[2,3-D]pyrimidin-4(8H)-one17 chemicals, 3 rings![Scaffold c1nnc(C2CCNCC2)[nH]1](/scaffold/YPPVPNFMCXRUCC-UHFFFAOYSA-N/structure.svg)
4-(4H-1,2,4-Triazol-3-yl)piperidine17 chemicals, 2 rings
2-(3-Oxothiomorpholin-2-yl)-N-phenylacetamide17 chemicals, 2 rings
O=C1C=CC2CC3OC(=O)CC4C5CCC(C2C1)C34CO517 chemicals, 5 rings
N-(4-(Benzoylamino)phenyl)benzamide16 chemicals, 3 rings
O=C(COc1ccccc1)N1CCc2ccccc2C116 chemicals, 3 rings
4-Benzoylpiperazin-2-one16 chemicals, 2 rings
LY-7349716 chemicals, 2 rings
O=C(C=Cc1ccc2c(c1)OCO2)c1ccccc116 chemicals, 3 rings
O=C1CCCC(OC2CCC(OC3CCCCO3)CO2)CCCCC=CC=CCCO116 chemicals, 3 rings
O=c1ccc2cccc3c2n1CCC316 chemicals, 3 rings
c1cc2c(s1)COCC216 chemicals, 2 rings
6,7-Dihydro-5H-cyclopenta(d)pyrimidine16 chemicals, 2 rings
O=C(COc1ccccc1)Nc1ccccc1C(=O)N1CCOCC116 chemicals, 3 rings
O=C1CC2C3CCCC3CCC2C2CCCCC1216 chemicals, 4 rings![Scaffold O=c1ccnc2nc(SCc3ccccc3)[nH]n12](/scaffold/CFJRMFOBOAXTAC-UHFFFAOYSA-N/structure.svg)
O=c1ccnc2nc(SCc3ccccc3)[nH]n1216 chemicals, 3 rings
N-(5-Oxo-1-phenylpyrrolidin-3-yl)benzenesulfonamide16 chemicals, 3 rings
1-Phenyl-3-((tetrahydrofuran-2-yl)methyl)thiourea16 chemicals, 2 rings
2,5-Diphenyloxazole16 chemicals, 3 rings
Pteridine16 chemicals, 2 rings
Azulene16 chemicals, 2 rings
2-(1H-Imidazol-1-yl)-1-phenylethanone16 chemicals, 2 rings![Scaffold N=c1[nH]c2nc3ccccn3c(=O)c2cc1C(=O)NC1CCCC1](/scaffold/DFJOJTSXTUBAKP-UHFFFAOYSA-N/structure.svg)
N=c1[nH]c2nc3ccccn3c(=O)c2cc1C(=O)NC1CCCC116 chemicals, 4 rings
1-(Furan-2-ylmethyl)-3-phenylurea16 chemicals, 2 rings![Scaffold c1cc(C2CCNCC2)[nH]n1](/scaffold/FCKYIGWJVZIPLK-UHFFFAOYSA-N/structure.svg)
4-(1H-Pyrazol-5-yl)piperidine16 chemicals, 2 rings
4-Phenyl-1,2,3,4-tetrahydroquinoxalin-2-one16 chemicals, 3 rings![Scaffold O=c1nc(-c2ccccc2)c2ccccc2[nH]1](/scaffold/FHUBTSLLILWICW-UHFFFAOYSA-N/structure.svg)
2(1H)-Quinazolinone, 4-phenyl-16 chemicals, 3 rings
1-(Phenylacetyl)piperidine16 chemicals, 2 rings
c1ccc(C2Oc3ccccc3C3=C2C(c2ccccc2)n2ncnc2N3)cc116 chemicals, 6 rings
N-[3-(1H-Tetrazol-1-yl)phenyl]benzenesulfonamide16 chemicals, 3 rings
O=c1cccnn1Cc1ccccc116 chemicals, 2 rings![Scaffold O=c1cccc2[nH]c3ccccc3n12](/scaffold/FWDLECMHULUHDO-UHFFFAOYSA-N/structure.svg)
O=c1cccc2[nH]c3ccccc3n1216 chemicals, 3 rings
Norcotinine16 chemicals, 2 rings
N-Cyclopropyl-N'-phenylurea16 chemicals, 2 rings
N-(4-Anilinophenyl)benzamide16 chemicals, 3 rings
3,4-Ethylenedioxythiophene16 chemicals, 2 rings
4-(Pyridin-3-yl)morpholine16 chemicals, 2 rings
c1ccc(-n2cnnc2-c2cccnc2)cc116 chemicals, 3 rings
1'-Benzoylspiro[chroman-2,4'-piperidin]-4-one16 chemicals, 4 rings
4-(1,3-Thiazol-2-yl)piperidine16 chemicals, 2 rings
O=C1C=C2C3CCCCC3CCC2C2CCC3CCCCC3C1216 chemicals, 5 rings
C1CCC2(CC3C(CC4C3CCC3C5CCCCC5CCC34)O2)OC116 chemicals, 6 rings
(9H-Fluoren-9-yl)methyl piperazine-1-carboxylate16 chemicals, 4 rings
1-Piperazinylpyrazine16 chemicals, 2 rings
4,6(1H,5H)-Pyrimidinedione16 chemicals, 1 ring
Benzamide, N-1-adamantyl-16 chemicals, 5 rings
N-Benzyl-1-(oxolan-2-yl)methanamine16 chemicals, 2 rings