Browse by ring system
Murcko scaffolds
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: its rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
- Scaffolds with a page
- 15.8K
- Distinct scaffolds computed
- 545.2K
Scaffolds with the most chemicals
Each scaffold here is shared by at least 3 chemicals with full pages. Very common single rings such as benzene and pyridine are left out.
Showing 2,041 to 2,100 of 15,838 scaffolds
Urea, n-phenyl-n'-2-thiazolyl-16 chemicals, 2 rings
c1ccc(Nc2ncnc3sccc23)cc116 chemicals, 3 rings
Diphenyl carbonate16 chemicals, 2 rings
O=c1ncccn1C1CSCO116 chemicals, 2 rings![Scaffold O=c1[nH]c2ccccc2c2ccccc12](/scaffold/RZFVLEJOHSLEFR-UHFFFAOYSA-N/structure.svg)
6(5H)-Phenanthridinone16 chemicals, 3 rings
O=C(CNC(=O)c1ccccc1)NN=Cc1ccco116 chemicals, 2 rings
2-((4-Oxo-6-((4-phenylpiperazin-1-yl)methyl)-4H-pyran-3-yl)oxy)-N-phenylacetamide16 chemicals, 4 rings
4-(1,3,4-Oxadiazol-2-yl)pyridine16 chemicals, 2 rings
c1cn2ncsc2n116 chemicals, 2 rings
O=c1cc(-c2cccc(-c3cccc4c(=O)cc(-c5ccccc5)oc34)c2)oc2ccccc1216 chemicals, 6 rings
O=C(COc1ccccc1)NN=Cc1ccc(OC(=O)C=Cc2ccccc2)cc116 chemicals, 3 rings
Bicyclo(2.2.2)oct-2-ene16 chemicals, 3 rings
C1=CC(c2ccccc2)C=CO116 chemicals, 2 rings
c1ccc2c(c1)NC1NCCC2116 chemicals, 3 rings
O=C(COc1ccccc1)Nc1nncs116 chemicals, 2 rings
C1COC(C2CC2)C116 chemicals, 2 rings
O=C1C=CCC(c2ccccc2)C116 chemicals, 2 rings
N-Phenylquinoline-4-carboxamide16 chemicals, 3 rings
O=C(CC1C(=O)NCCN1C(=O)c1ccccc1)Nc1ccccc116 chemicals, 3 rings
N-[4-(4-Morpholinylsulfonyl)phenyl]-2-phenoxyacetamide16 chemicals, 3 rings
N-Phenyl-2-[(3-pyridin-2-yl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)sulfanyl]acetamide16 chemicals, 4 rings
O=C(Nc1ccccc1)c1cnc2sccn2c1=O16 chemicals, 3 rings
O=C1C=C2CCC3C4CCCC4CC(=O)C3C2CC116 chemicals, 4 rings
O=C(COc1ccccc1)NN=Cc1cccc(OCc2ccccc2)c116 chemicals, 3 rings
1-(Thiazol-2-yl)piperazine16 chemicals, 2 rings
1-Cyclopentylpiperidine16 chemicals, 2 rings
N-Phenyl-2-((3-(pyridin-3-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)acetamide16 chemicals, 4 rings
O=C(Nc1cc2c(s1)CCCCC2)c1ccccc116 chemicals, 3 rings
3-Benzyl-1,2,4-oxadiazole16 chemicals, 2 rings
4-Phenylcyclohexene16 chemicals, 2 rings![Scaffold O=C(Nc1ccccn1)c1cc2ccccc2[nH]c1=O](/scaffold/XWUHUGDHABUZRH-UHFFFAOYSA-N/structure.svg)
O=C(Nc1ccccn1)c1cc2ccccc2[nH]c1=O16 chemicals, 3 rings
N,N'-Terephthalylidenedianiline16 chemicals, 3 rings
1-Benzoyl-4-phenyl-3-thiosemicarbazide16 chemicals, 2 rings![Scaffold O=c1[nH]c2ncccc2c(=O)n1Cc1ccccc1](/scaffold/YLODREUTFHMXIW-UHFFFAOYSA-N/structure.svg)
LC3B ligand 116 chemicals, 3 rings
1-H-Azepine, hexahydro-1-phenyl16 chemicals, 2 rings
N-(4-Morpholin-4-ylphenyl)benzamide16 chemicals, 3 rings
Canthin-6-one16 chemicals, 4 rings
RefChem:38150516 chemicals, 5 rings
3-Phenyl-N-(1,3-thiazol-2-yl)propanamide16 chemicals, 2 rings
2-[(2-Oxo-2-phenylethyl)sulfanyl]-3-phenylquinazolin-4(3H)-one16 chemicals, 4 rings
O=C(Nc1cccs1)c1cccs116 chemicals, 2 rings
O=C1Nc2ccccc2C1=C1SC(=S)N(Cc2ccccc2)C1=O15 chemicals, 4 rings
O=C(C1=CC(=O)N(c2ccon2)C1c1ccccc1)c1cc2ccccc2o115 chemicals, 5 rings
[1,2,3]Triazolo[1,5-a]pyridine15 chemicals, 2 rings
O=C(NN=Cc1ccccc1)C1CCCCC115 chemicals, 2 rings
1-(4-Morpholinyl)-3-phenyl-2-propen-1-one15 chemicals, 2 rings
N-(5,5-Dioxo-2-phenyl-4,6-dihydrothieno[3,4-c]pyrazol-3-yl)-2-phenoxyacetamide15 chemicals, 4 rings
(3,5-Diphenyl-4,5-dihydro-1H-pyrazol-1-yl)(phenyl)methanone15 chemicals, 4 rings
2-Oxo-N-(phenylmethyl)-2H-1-benzopyran-3-carboxamide15 chemicals, 3 rings
O=C1CC2CCCC2C2CCC3CCCCC3C1215 chemicals, 4 rings
O=C1C(=Cc2ccccc2)C=NN1c1ccccc115 chemicals, 3 rings![Scaffold c1ccc2c3c([nH]c2c1)COCC3](/scaffold/BJJRXQKRTYZXDU-UHFFFAOYSA-N/structure.svg)
c1ccc2c3c([nH]c2c1)COCC315 chemicals, 3 rings
4-Cyclopropyl-4H-1,2,4-triazole15 chemicals, 2 rings
N=C1C=CC2C(=O)OC3CC(CC=CC(OC4CCCCO4)CC=CC=C4COC1C42)OC1(CCCC(C2CCCCC2)O1)C315 chemicals, 7 rings
3-(Piperidin-4-yl)pyridine15 chemicals, 2 rings
6,7-Dihydro-5H-pyrrolo[2,1-c][1,2,4]triazole15 chemicals, 2 rings
N-Nicotinylbenzylamine15 chemicals, 2 rings
O=C(CCc1ccccc1)NCC(=O)NCCc1ccccc115 chemicals, 2 rings
O=C(Nc1ccccc1N1CCOCC1)c1ccccc115 chemicals, 3 rings
1-Benzylazetidine15 chemicals, 2 rings