Browse by ring system
Murcko scaffolds
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: its rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
- Scaffolds with a page
- 15.8K
- Distinct scaffolds computed
- 545.2K
Scaffolds with the most chemicals
Each scaffold here is shared by at least 3 chemicals with full pages. Very common single rings such as benzene and pyridine are left out.
Showing 2,161 to 2,220 of 15,838 scaffolds
![Scaffold S=c1[nH]ncn1NCc1ccccc1](/scaffold/KUJRVYTXNDZJRX-UHFFFAOYSA-N/structure.svg)
S=c1[nH]ncn1NCc1ccccc115 chemicals, 2 rings
O=C(C=Cc1ccccc1)OC1COC(OCCc2ccccc2)CC1OC1CCCCO115 chemicals, 4 rings![Scaffold O=c1[nH]c(=O)c2[nH]c(=O)[nH]c2[nH]1](/scaffold/LEHOTFFKMJEONL-UHFFFAOYSA-N/structure.svg)
Uric acid15 chemicals, 2 rings
Benzyl cyclopropanecarboxylate15 chemicals, 2 rings
2-(Naphthalen-2-yl)-1,3,2-dioxaborolane15 chemicals, 3 rings
O=C(C=Cc1ccccc1)Nc1cccnc115 chemicals, 2 rings
C1=CC2C(C=COC2OC2CCCCO2)C115 chemicals, 3 rings
1-Cyclopentyl-3-phenylthiourea15 chemicals, 2 rings
O=C(CCNc1ccccc1)c1ccc(-c2ccccc2)cc115 chemicals, 3 rings
1-(2-Thienylsulfonyl)pyrrolidine15 chemicals, 2 rings
3-(1,2,4-Oxadiazol-3-yl)pyridine15 chemicals, 2 rings
3-Benzoylcoumarin15 chemicals, 3 rings
1,2,3,4-Tetrahydrodibenzofuran15 chemicals, 3 rings
O=C(COC(=O)c1cccnc1)NC1CCCCC115 chemicals, 2 rings
O=C1CNC(=O)CNC(=O)C(Cc2ccccc2)NC(=O)CCSSCC(C(=O)N2CCCC2)NC(=O)CN115 chemicals, 3 rings
O=C(CCNc1ccccc1)c1ccc2ccccc2c115 chemicals, 3 rings![Scaffold O=C(NCCc1c[nH]c2ccccc12)OCC1c2ccccc2-c2ccccc21](/scaffold/MGQVRMQUYJGNLP-UHFFFAOYSA-N/structure.svg)
O=C(NCCc1c[nH]c2ccccc12)OCC1c2ccccc2-c2ccccc2115 chemicals, 5 rings
N-Benzylidenebenzylamine15 chemicals, 2 rings
c1ccc(Nc2ncnc(CN3CCCCC3)n2)cc115 chemicals, 3 rings
3-(Phenylamino)-1-(2-thienyl)-1-propanone15 chemicals, 2 rings![Scaffold O=c1[nH]cnnc1-c1ccccc1](/scaffold/MVAQKCBXFGRWER-UHFFFAOYSA-N/structure.svg)
O=c1[nH]cnnc1-c1ccccc115 chemicals, 2 rings
4-Cyclopropylpiperidine15 chemicals, 2 rings![Scaffold O=C(c1ccccc1)c1ccc[nH]1](/scaffold/NFGGQMYSOLVBLF-UHFFFAOYSA-N/structure.svg)
Phenyl(1H-pyrrol-2-yl)methanone15 chemicals, 2 rings
4-(4-Phenyl-4H-1,2,4-triazol-3-yl)pyridine15 chemicals, 3 rings![Scaffold O=c1[nH]c(=O)c2c(ncn2CCOc2ccccc2)[nH]1](/scaffold/NHEHGYKCFDHWBC-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2c(ncn2CCOc2ccccc2)[nH]115 chemicals, 3 rings
N-[(E)-2-Thienylmethylidene]aniline15 chemicals, 2 rings![Scaffold C1=NCCc2c1[nH]c1ccccc21](/scaffold/NTYXKFHKVREUMR-UHFFFAOYSA-N/structure.svg)
3H-Pyrido(3,4-b)indole, 4,9-dihydro-15 chemicals, 3 rings
O=C(CNC(=O)c1ccccc1)NN=Cc1cccc2ccccc1215 chemicals, 3 rings
N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-phenoxyacetamide15 chemicals, 3 rings
N-(1,3-Benzodioxol-5-yl)-2-phenoxyacetamide15 chemicals, 3 rings
N-(Pyridin-3-ylmethylcarbamothioyl)benzamide15 chemicals, 2 rings
1-Benzyl-1H-benzotriazole15 chemicals, 3 rings
Phenethyl benzoate15 chemicals, 2 rings
2-Oxa-8-azaspiro(4.5)decane15 chemicals, 2 rings
2,6-Di(phenyl)-4-piperidone15 chemicals, 3 rings
3-Phenyl-oxindole15 chemicals, 3 rings
1-Cyclohexyl-3-phenyl-2-thiourea15 chemicals, 2 rings
N-(2-Oxo-2,4,5,6-tetrahydro-1H-pyrrolo[3,2,1-ij]quinolin-8-yl)benzenesulfonamide15 chemicals, 4 rings
N-2-Benzothiazolylbenzeneacetamide15 chemicals, 3 rings
3-Cyclohexylpyrrolidine15 chemicals, 2 rings![Scaffold c1ccc(CSc2nc3ccccc3[nH]2)nc1](/scaffold/PLITYYGQMDTHMM-UHFFFAOYSA-N/structure.svg)
2-((Pyridin-2-ylmethyl)thio)-1H-benzo[d]imidazole15 chemicals, 3 rings
O=C(C=Cc1cccs1)Nc1ccccc115 chemicals, 2 rings
Benzene, 1,1'-(1,5-pentanediylbis(oxy))bis-15 chemicals, 2 rings
2-Azaspiro(3.4)octane15 chemicals, 2 rings
O=C(NC1CCCC1)OCC1c2ccccc2-c2ccccc2115 chemicals, 4 rings
C=C1CC23CCC4CCCCC4C2CCC1C315 chemicals, 4 rings
O=S(=O)(Nc1ccccc1)c1cccc2cccnc1215 chemicals, 3 rings
O=C(NCC1CCCCO1)C1CCCN115 chemicals, 2 rings
O=C(COC(=O)c1cccnc1)NCc1ccccc115 chemicals, 2 rings
O=C(CCS(=O)(=O)c1ccccc1)Nc1nnc(-c2ccccc2)o115 chemicals, 3 rings
Naphtho(2,3-b)furan-4,9-dione15 chemicals, 3 rings
O=C(Nc1ccccc1)c1csc2c1CCCC215 chemicals, 3 rings
3,4-Dihydro-2H-pyrido(3,2-b)(1,4)oxazine15 chemicals, 2 rings
1-(2-Phenoxyethyl)pyrrolidine15 chemicals, 2 rings
Azocan15 chemicals, 1 ring
N1-benzyl-N2-((3-(phenylsulfonyl)oxazolidin-2-yl)methyl)oxalamide15 chemicals, 3 rings
2,5-Diaziridinyl-1,4-benzoquinone15 chemicals, 3 rings
O=C(CCCc1ccccc1)N1CCn2cnnc2C115 chemicals, 3 rings
1,3,5-Triazine, 2-(4-morpholinyl)-15 chemicals, 2 rings
2-Phenyl-N-(4-phenyl-1,3-thiazol-2-yl)acetamide15 chemicals, 3 rings