Browse by ring system
Murcko scaffolds
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: its rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
- Scaffolds with a page
- 15.8K
- Distinct scaffolds computed
- 545.2K
Scaffolds with the most chemicals
Each scaffold here is shared by at least 3 chemicals with full pages. Very common single rings such as benzene and pyridine are left out.
Showing 2,821 to 2,880 of 15,838 scaffolds
2H-1-Benzopyran-3-carboxylic acid, 2-oxo-, phenyl ester12 chemicals, 3 rings![Scaffold O=c1[nH]cnc2c1oc1ccccc12](/scaffold/PCCWPSFTRGJXEF-UHFFFAOYSA-N/structure.svg)
8-Oxa-3,5-diazatricyclo[7.4.0.0,2,7]trideca-1(13),2(7),3,9,11-pentaen-6-one12 chemicals, 3 rings
O=C1CC2CCC(=O)C2C2=C1C1CCCCC1CC212 chemicals, 4 rings
N-(2-Benzylphenyl)benzamide12 chemicals, 3 rings
AI-020/1277200112 chemicals, 2 rings![Scaffold c1cc2occc2[nH]1](/scaffold/PLJIVNLEQUBQTH-UHFFFAOYSA-N/structure.svg)
4H-Furo(3,2-b)pyrrole12 chemicals, 2 rings![Scaffold O=C(Nc1nn[nH]n1)c1ccccc1](/scaffold/PLTCINJSRCMVPL-UHFFFAOYSA-N/structure.svg)
N-(1H-Tetrazol-5-yl)benzamide12 chemicals, 2 rings
N1-phenyl-N2-(2-(1-(phenylsulfonyl)piperidin-2-yl)ethyl)oxalamide12 chemicals, 3 rings
1,4-Diphenoxybutane12 chemicals, 2 rings
Piperazine, 1-benzyl-4-(2-pyridyl)-12 chemicals, 3 rings
Spiro(1,3-dioxolane-2,3'-(3H)indol)-2'(1'H)-one12 chemicals, 3 rings
N-(Oxolan-2-ylmethyl)-N'-phenyloxamide12 chemicals, 2 rings
C1CCN2CC3C(CCC4C3CC35OC6CCCC3C6CCC45)CC2C112 chemicals, 7 rings
4-(Morpholine-4-sulfonyl)-N-phenyl-benzamide12 chemicals, 3 rings
O=C(NCC(c1cccs1)N1CCOCC1)c1ccccc112 chemicals, 3 rings
C1CC2CCOC2C112 chemicals, 2 rings
N'-Pyridin-2-ylbenzohydrazide12 chemicals, 2 rings
c1cnc(C2CCC2)nc112 chemicals, 2 ringsO1)O[PH](=O)OCC1CCC(n2cnc3cncnc32)O1](/scaffold/QMVHHVSTFIPFPP-UHFFFAOYSA-N/structure.svg)
O=[PH](OCC1CCC(N2C=CCC=C2)O1)O[PH](=O)OCC1CCC(n2cnc3cncnc32)O112 chemicals, 5 rings
Benzyl(cyclopropylmethyl)amine12 chemicals, 2 rings
O=C(Cc1ccccc1)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc112 chemicals, 3 rings
N-2-Pyridinyl-3-pyridinecarboxamide12 chemicals, 2 rings
O=C(Cc1cccc2ccccc12)NN=Cc1ccc(OC(=O)c2ccccc2)cc112 chemicals, 4 rings
2-((4-Oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-phenylacetamide12 chemicals, 4 rings![Scaffold O=C(Cc1n[nH]c(=O)c2ccccc12)Nc1ccccc1](/scaffold/RCKILYGUNWZTBY-UHFFFAOYSA-N/structure.svg)
O=C(Cc1n[nH]c(=O)c2ccccc12)Nc1ccccc112 chemicals, 3 rings
c1ccc(-c2nnn3c2ncc2ccccc23)cc112 chemicals, 4 rings
1,3-Dibenzyloxybenzene12 chemicals, 3 rings![Scaffold O=C(NCCc1cc2ccccc2[nH]c1=O)c1ccccc1](/scaffold/RLWQKKJAXJDFAZ-UHFFFAOYSA-N/structure.svg)
O=C(NCCc1cc2ccccc2[nH]c1=O)c1ccccc112 chemicals, 3 rings
9-Benzylidenefluorene12 chemicals, 4 rings
2,3-Diphenyl-4(3H)-quinazolinone12 chemicals, 4 rings![Scaffold O=c1[nH]cnc2c1N=CCN2](/scaffold/RSPZIHWNURGJFC-UHFFFAOYSA-N/structure.svg)
4(3H)-Pteridinone, 7,8-dihydro-12 chemicals, 2 rings
Piperidine, 1-(2-phenoxyethyl)-12 chemicals, 2 rings![Scaffold O=S(=O)(Nc1ccc2cn[nH]c2c1)c1ccccc1](/scaffold/RTTZPLJQEYPLQB-UHFFFAOYSA-N/structure.svg)
O=S(=O)(Nc1ccc2cn[nH]c2c1)c1ccccc112 chemicals, 3 rings
N-(3-Benzamidophenyl)furan-2-carboxamide12 chemicals, 3 rings
c1ccc(C2OCC3OCCCC3O2)cc112 chemicals, 3 rings
O=C(Nc1nc2ccccc2s1)C1COc2ccccc2O112 chemicals, 4 rings
O=C(c1ccco1)N1CCN(C(=S)Nc2ccccc2)CC112 chemicals, 3 rings
O=S(=O)(Nc1ccc(-c2ccc3nncn3n2)cc1)c1ccccc112 chemicals, 4 rings
2-(4-Phenylpiperazine-1-carbonyl)-4H-chromen-4-one12 chemicals, 4 rings
Sbb04238512 chemicals, 2 rings
3-Phenylphthalide12 chemicals, 3 rings
1-Phenylmethanesulfonyl-piperidine12 chemicals, 2 rings
Benzoic acid, 4-(benzoyloxy)-, phenyl ester12 chemicals, 3 rings
1-(Phenylacetyl)pyrrolidine12 chemicals, 2 rings
O=C(Nc1ccno1)c1ccccc112 chemicals, 2 rings
O=c1c(-c2ccccc2)coc2c(CN3CCNCC3)cccc1212 chemicals, 4 rings
O=C1NC(=O)C(=Cc2ccccc2)N112 chemicals, 2 rings
3-(3-Phenoxypropyl)-1,3-benzoxazol-2(3H)-one12 chemicals, 3 rings
C1=CC(=C(c2ccccc2)c2ccc(NCc3ccccc3)cc2)C=CC1=NCc1ccccc112 chemicals, 5 rings
N-[2-(Morpholine-4-carbonyl)phenyl]benzamide12 chemicals, 3 rings
4-(Phenylacetyl)morpholine12 chemicals, 2 rings
4-(Benzenesulfonyl)-1,3-dihydroquinoxalin-2-one12 chemicals, 3 rings
O=C(c1ccccc1)N1CCN(c2ncccn2)CC112 chemicals, 3 rings
N-[Benzo[d]thiazol-2-yl]nicotinamide12 chemicals, 3 rings![Scaffold O=c1ccn(S(=O)(=O)c2ccccc2)[nH]1](/scaffold/UYFFQNWWNGRYBJ-UHFFFAOYSA-N/structure.svg)
O=c1ccn(S(=O)(=O)c2ccccc2)[nH]112 chemicals, 2 rings
O=C1CCCC2=C1C(c1ccsc1)C(C(=O)Nc1ccccn1)=CN212 chemicals, 4 rings
Hexamethylenetetramine12 chemicals, 4 rings
Morpholine, 4-(2-phenylethyl)-12 chemicals, 2 rings
2-(2-Phenylethyl)chromone12 chemicals, 3 rings
O=C(C=Cc1ccccc1)NC1CCCCC112 chemicals, 2 rings