Browse by ring system
Murcko scaffolds
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: its rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
- Scaffolds with a page
- 15.8K
- Distinct scaffolds computed
- 545.2K
Scaffolds with the most chemicals
Each scaffold here is shared by at least 3 chemicals with full pages. Very common single rings such as benzene and pyridine are left out.
Showing 1,741 to 1,800 of 15,838 scaffolds
O=C(c1ccccc1)N1CCN(S(=O)(=O)c2ccccc2)CC118 chemicals, 3 rings
O=C1C(=Cc2ccccc2)CCc2ccccc2118 chemicals, 3 rings
Benzathine18 chemicals, 2 rings
8-Oxa-2-azaspiro(4.5)decane18 chemicals, 2 rings
N-Phenyl[1,1'-biphenyl]-2-carboxamide18 chemicals, 3 rings
1-Phenyl-3-(thiophen-2-ylmethyl)thiourea18 chemicals, 2 rings
Piperazine, 1-phenyl-4-(2-thenoyl)-18 chemicals, 3 rings
O=C(C=Cc1ccccc1)NC(=S)Nc1ccccc118 chemicals, 2 rings
2H-Pyran, 2-(cyclohexyloxy)tetrahydro-18 chemicals, 2 rings
2-(Piperidin-4-yl)pyridine18 chemicals, 2 rings
N-(1-(Phenylmethyl)-4-piperidinyl)benzamide18 chemicals, 3 rings
c1ccc(OCCCN2CCCCC2)cc118 chemicals, 2 rings
3-Azaspiro(5.5)undecane hydrochloride18 chemicals, 2 rings![Scaffold S=c1[nH]nc(Cc2ccccc2)[nH]1](/scaffold/MAGFPLALYSZUTR-UHFFFAOYSA-N/structure.svg)
5-Benzyl-2,3-dihydro-1H-1,2,4-triazole-3-thione18 chemicals, 2 rings
Dibenzyl ether18 chemicals, 2 rings
O=C1CCCC2=C1C(c1cccnc1)C=CN2c1ccccc118 chemicals, 4 rings
Imidazo(1,5-a)pyrazine18 chemicals, 2 rings
2,3-Dihydro-1,4-benzodioxin-6-yl(phenyl)methanone18 chemicals, 3 rings
4-Piperidinopyridine18 chemicals, 2 rings
O=C(C=Cc1cccs1)Nc1nc2ccccc2s118 chemicals, 3 rings![Scaffold c1ccc(C[n+]2ccccc2)cc1](/scaffold/NDZFNTHGIIQMQI-UHFFFAOYSA-N/structure.svg)
1-(Phenylmethyl)pyridinium18 chemicals, 2 rings
O=C(C1=CC(=O)N(c2nncs2)C1c1ccccc1)c1ccco118 chemicals, 4 rings
N-(1-Naphthyl)-N-(phenylmethylene)amine18 chemicals, 3 rings![Scaffold O=c1cc[nH]c2ncccc12](/scaffold/NQUIRWXTTAMWIU-UHFFFAOYSA-N/structure.svg)
1,8-Naphthyridin-4-ol18 chemicals, 2 rings
4,5-Diphenyloxazole18 chemicals, 3 rings
O=C(NN=Cc1ccccc1)c1ccccc1NS(=O)(=O)c1ccccc118 chemicals, 3 rings
4-Phenyl-1,2,3,4-tetrahydro-isoquinoline18 chemicals, 3 rings![Scaffold c1ccc(Nc2nc3ccccc3[nH]2)cc1](/scaffold/OUAAURDVPDKVAK-UHFFFAOYSA-N/structure.svg)
(1H-Benzoimidazol-2-yl)-phenyl-amine18 chemicals, 3 rings![Scaffold c1ccc2c3c([nH]c2c1)C1CCCCN1CC3](/scaffold/OURDZMSSMGUMKR-UHFFFAOYSA-N/structure.svg)
1,2,3,4,6,7,12,12b-Octahydroindolo(2,3-a)quinolizine18 chemicals, 4 rings
3-Phenoxypiperidine18 chemicals, 2 rings![Scaffold O=C(c1cccc2ccccc12)c1c[nH]c2ccccc12](/scaffold/QIXQGVQLBPQVOR-UHFFFAOYSA-N/structure.svg)
3-Naphthoylindole18 chemicals, 4 rings
Azobenzene, 4-(phenylazo)-18 chemicals, 3 rings
O=C1CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CN118 chemicals, 1 ring
1,4-Diazepan-5-one18 chemicals, 1 ring
2-Phenylisoindoline18 chemicals, 3 rings![Scaffold S=c1[nH]nc(COc2ccccc2)[nH]1](/scaffold/RDUDDGORNKMCCT-UHFFFAOYSA-N/structure.svg)
S=c1[nH]nc(COc2ccccc2)[nH]118 chemicals, 2 rings
c1ccc(Oc2ccnc(-c3ccccc3)n2)cc118 chemicals, 3 rings![Scaffold O=c1c(-c2ccccc2)c[nH]c2ccccc12](/scaffold/RLLYMKQAMJFPDL-UHFFFAOYSA-N/structure.svg)
3-Phenylquinolin-4(1H)-one18 chemicals, 3 rings
4-Benzyl-N-phenylpiperazine-1-carbothioamide18 chemicals, 3 rings
3-Phenylimidazolidine-2,4-dione18 chemicals, 2 rings
C1=C2CCCCC2C2CCC3CCCC3C2=C118 chemicals, 4 rings
O=C(Cn1cccn1)Nc1ccccc118 chemicals, 2 rings
2-Azaspiro(4.5)decane18 chemicals, 2 rings
O=C1NC=CC(c2ccc3c(c2)OCO3)N118 chemicals, 3 rings
4-Benzylamino-4H-1,2,4-triazole18 chemicals, 2 rings
O=C(COc1ccccc1)Nc1cccs118 chemicals, 2 rings![Scaffold N=c1[nH]c2nc3ccccn3c(=O)c2cc1C(=O)NC1CCCCC1](/scaffold/STCWXONUXNCLNQ-UHFFFAOYSA-N/structure.svg)
N=c1[nH]c2nc3ccccn3c(=O)c2cc1C(=O)NC1CCCCC118 chemicals, 4 rings
O=C(CN1CCCCCC1)Nc1ccccc118 chemicals, 2 rings
N-(Pyridin-4-yl)benzenesulfonamide18 chemicals, 2 rings![Scaffold O=c1[nH]c(SCc2ccccc2)nc2ccccc12](/scaffold/UGTCWCXNSKYVOL-UHFFFAOYSA-N/structure.svg)
RefChem:38228618 chemicals, 3 rings![Scaffold c1ccc(Nc2ncnc3[nH]ncc23)cc1](/scaffold/UOIOGRJMBMHOJZ-UHFFFAOYSA-N/structure.svg)
c1ccc(Nc2ncnc3[nH]ncc23)cc118 chemicals, 3 rings![Scaffold O=c1ccc2cn[nH]c2[nH]1](/scaffold/USFSKUQFHBPJNW-UHFFFAOYSA-N/structure.svg)
1H-Pyrazolo[3,4-b]pyridin-6-ol18 chemicals, 2 rings
3-Cyclopropylthiophene18 chemicals, 2 rings
O=C(CCCN1CCC(c2ccccc2)CC1)c1ccccc118 chemicals, 3 rings
C1CC2(C1)CCOC218 chemicals, 2 rings
O=C(Nc1nnc(-c2ccccc2)o1)c1ccccc118 chemicals, 3 rings
3-Benzylpyridazine18 chemicals, 2 rings
2-Phenyl-N-(phenylcarbamothioyl)acetamide18 chemicals, 2 rings
N-Phenyl-3-thiophenecarboxamide18 chemicals, 2 rings
1,2-Diphenyl-3,5-pyrazolidinedione18 chemicals, 3 rings