Browse by ring system
Murcko scaffolds
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: its rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
- Scaffolds with a page
- 15.8K
- Distinct scaffolds computed
- 545.2K
Scaffolds with the most chemicals
Each scaffold here is shared by at least 3 chemicals with full pages. Very common single rings such as benzene and pyridine are left out.
Showing 1,621 to 1,680 of 15,838 scaffolds
2-Phenoxy-N-(2-pyridinyl)acetamide19 chemicals, 2 rings
Piperidine, 1-(2-phenylethyl)-19 chemicals, 2 rings
4-Phenyl-3,4-dihydroquinolin-2(1H)-one19 chemicals, 3 rings
Cyclohexyl benzoate19 chemicals, 2 rings
O=C(CCN1C(=O)c2ccccc2S1(=O)=O)Nc1ccccc119 chemicals, 3 rings![Scaffold c1ccc(-c2nc3ncccc3[nH]2)cc1](/scaffold/DYKJXWALYRGLPF-UHFFFAOYSA-N/structure.svg)
2-Phenylimidazo(4,5-b)pyridine19 chemicals, 3 rings![Scaffold c1cc(-c2cc[nH]n2)ccn1](/scaffold/FEBRHATXLQPYLJ-UHFFFAOYSA-N/structure.svg)
4-(1H-Pyrazol-3-yl)pyridine19 chemicals, 2 rings
4-(1-Adamantyl)-1,3-thiazole19 chemicals, 5 rings![Scaffold O=c1[nH]nc(-c2ccccc2)[nH]1](/scaffold/FFSXNTGAFSVILG-UHFFFAOYSA-N/structure.svg)
3-Phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one19 chemicals, 2 rings
Triphenylphosphine oxide19 chemicals, 3 rings
C1=CC(c2ccccc2)C=CS119 chemicals, 2 rings
Benzoic acid, 2-(2-furanylmethylene)hydrazide19 chemicals, 2 rings![Scaffold O=c1[nH]c(=O)c2[nH]c(N3CCCCC3)nc2[nH]1](/scaffold/FUGSLBPVJWSROG-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]c(N3CCCCC3)nc2[nH]119 chemicals, 3 rings
2-Phenoxy-1-(pyrrolidin-1-yl)ethan-1-one19 chemicals, 2 rings
O=C(NN1C(=O)C(=Cc2ccccc2)SC1=S)c1ccccc119 chemicals, 3 rings
Urea, N-phenyl-N'-1,3,4-thiadiazol-2-yl-19 chemicals, 2 rings
O=S(=O)(Nc1ccc2occc2c1)c1ccccc119 chemicals, 3 rings
O=C(CN=Nc1ccc(-c2ccc(N=NCC(=O)Nc3ccccc3)cc2)cc1)Nc1ccccc119 chemicals, 4 rings
9-Phenyl-3,4,5,6,7,9-hexahydro-2H-xanthene-1,8-dione19 chemicals, 4 rings
Pyrrolidin-1-yl(pyrrolidin-2-yl)methanone19 chemicals, 2 rings
2-(Phenoxymethyl)pyridine19 chemicals, 2 rings
c1ccc(CN2CCc3ccsc3C2)cc119 chemicals, 3 rings
(±)-Tetramisole19 chemicals, 3 rings
c1ccc(-c2cc(N3CCCCC3)c3ccccc3n2)cc119 chemicals, 4 rings
N-(2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-(furan-2-yl)ethyl)benzamide19 chemicals, 4 rings
N1-phenyl-N2-((1-(thiophen-2-ylsulfonyl)pyrrolidin-2-yl)methyl)oxalamide19 chemicals, 3 rings
Methyleneoxindole19 chemicals, 2 rings
c1ccc2c(c1)CCCCc1cc3c(cc1-2)OCO319 chemicals, 4 rings
c1ccc2c(c1)oc1cncnc1219 chemicals, 3 rings
Coumestan19 chemicals, 4 rings
2-Phenylindolizine19 chemicals, 3 rings
c1cc(B2OCCO2)cc(C2CC2)c119 chemicals, 3 rings
1,4-Bis(phenylsulfonyl)piperazine19 chemicals, 3 rings
c1cn(C2CCCO2)cn119 chemicals, 2 rings
O=C(C=Cc1ccccc1)N1CCCCC119 chemicals, 2 rings
O=C(Nc1ccc(S(=O)(=O)Nc2ccccc2)cc1)c1ccccc119 chemicals, 3 rings
1-Oxa-8-azaspiro(4.5)decane19 chemicals, 2 rings
C=C1CC23CCC4CCC(OC5CCCCO5)CC4C2CCC1C319 chemicals, 5 rings
1-(1,3-Benzothiazol-2-yl)-3-phenylurea19 chemicals, 3 rings
4-(3-Phenylpropyl)morpholine19 chemicals, 2 rings
O=C(Cc1ccccc1)NN=Cc1ccc(OC(=O)c2ccccc2)cc119 chemicals, 3 rings
N-Phenethyl phthalimide19 chemicals, 3 rings
1-(3-Thienyl)-1H-pyrrole19 chemicals, 2 rings
N,N'-Diphenylterephthalamide19 chemicals, 3 rings
O=C(OC1CCCCO1)C12CCCCC1C1=CCC3C4CCCCC4CCC3C1CC219 chemicals, 6 rings
(±)-Benzomorphan19 chemicals, 3 rings
C1CC2CCC34CC35CCCCC5CCC4C2C119 chemicals, 5 rings![Scaffold O=c1cnnc(SCc2ccccc2)[nH]1](/scaffold/NWXGZONMDISUET-UHFFFAOYSA-N/structure.svg)
3-(Benzylsulfanyl)-1,2,4-triazin-5-ol19 chemicals, 2 rings
O=C1Nc2cccnc2Nc2ncccc2119 chemicals, 3 rings
O=C(Nc1nnco1)c1ccccc119 chemicals, 2 rings
1,2,3,4,4a,5,6,7-Octahydronaphthalene19 chemicals, 2 rings
O=C(NC1C(=O)N2CCSC12)c1conc1-c1ccccc119 chemicals, 4 rings
O=C1OCC(Cc2ccccc2)C1Cc1ccccc119 chemicals, 3 rings
O=C(CCS(=O)(=O)c1ccccc1)Nc1ccccc119 chemicals, 2 rings
2-Phenylisoquinoline-1,3(2H,4H)-dione19 chemicals, 3 rings![Scaffold S=c1[nH]c(-c2ccccc2)cn1-c1ccccc1](/scaffold/QKOAQVKXZJFMET-UHFFFAOYSA-N/structure.svg)
Krm-iii19 chemicals, 3 rings
O=C(NCc1ccccc1)c1conc1-c1ccccc119 chemicals, 3 rings
c1ccc2c(c1)CCN1CCCCC2119 chemicals, 3 rings
Anthrone19 chemicals, 3 rings
2-Azabicyclo[4.1.0]heptane19 chemicals, 2 rings