Browse by ring system
Murcko scaffolds
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: its rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
- Scaffolds with a page
- 15.8K
- Distinct scaffolds computed
- 545.2K
Scaffolds with the most chemicals
Each scaffold here is shared by at least 3 chemicals with full pages. Very common single rings such as benzene and pyridine are left out.
Showing 2,461 to 2,520 of 15,838 scaffolds
1-(1,1-Dioxidotetrahydrothiophen-3-yl)-3-phenylurea14 chemicals, 2 rings![Scaffold O=c1[nH]c(=O)n(Cc2ccccc2)c2[nH]cnc12](/scaffold/YWCSDTAKJJLSPO-UHFFFAOYSA-N/structure.svg)
3-Benzyl-1H-purine-2,6(3H,7H)-dione14 chemicals, 3 rings
C1=CC2=CCCCC2CC114 chemicals, 2 rings
1-(Piperidin-4-yl)piperazine14 chemicals, 2 rings
O=C(COc1ccc2occc2c1)c1ccccc114 chemicals, 3 rings
O=C(Nc1ccccc1)C1CCN(C(=O)c2ccccc2)CC114 chemicals, 3 rings
O=C(CNCCCc1ccccc1)N1CCCC114 chemicals, 2 rings
1-Cyclohexyl-1H-1,3-benzodiazole14 chemicals, 3 rings![Scaffold c1ccc2[nH]c(C3CCCCC3)nc2c1](/scaffold/ZUKYCLYMFNPDCT-UHFFFAOYSA-N/structure.svg)
2-Cyclohexyl-1H-1,3-benzodiazole14 chemicals, 3 rings
O=C(Cc1cccc2ccccc12)Nc1ccccc114 chemicals, 3 rings
2(3H)-Benzofuranone13 chemicals, 2 rings![Scaffold O=C(c1ccccc1)c1c[nH]c2ccccc12](/scaffold/ADHQLIGSIQGNBW-UHFFFAOYSA-N/structure.svg)
3-Benzoylindole13 chemicals, 3 rings
Thiobenzoylmorpholine13 chemicals, 2 rings
1-{1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl}piperidine13 chemicals, 4 rings
O=C1CCCCCCCCCCCCCCC=CC=CC=CC=CC=CCCO113 chemicals, 1 ring
O=C(COc1ccccc1)Nc1ccc(N2CCNCC2)cc113 chemicals, 3 rings
1-Phenyl-3-[2-(piperidin-1-yl)ethyl]urea13 chemicals, 2 rings
N-(2-(Benzo[d][1,3]dioxol-5-yl)-2-morpholinoethyl)benzenesulfonamide13 chemicals, 4 rings
c1ccc(C2=NN3C(C2)c2ccccc2OC32CCNCC2)cc113 chemicals, 5 rings
9,9-Diphenylfluorene13 chemicals, 5 rings
1,6-Diphenoxyhexane13 chemicals, 2 rings
Hydrindane13 chemicals, 2 rings
1-(1,3-Benzodioxol-5-ylmethyl)-4-benzylpiperazine13 chemicals, 4 rings
2-[6-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-4-oxopyran-3-yl]oxy-N-phenylacetamide13 chemicals, 4 rings
N-(1,1-Dioxothiolan-3-yl)-2-phenoxyacetamide13 chemicals, 2 rings
O=C(c1ccccc1)c1ccc2c3ccccc3ccn1213 chemicals, 4 rings
O=C1OCOC(=O)C1=CNc1ccccc113 chemicals, 2 rings
O=C(COc1ccccc1)NC1CCCC113 chemicals, 2 rings
2'-Phenylbenzohydrazide13 chemicals, 2 rings
N,2-diphenylquinazolin-4-amine13 chemicals, 4 rings
c1ncn(C2CCCO2)n113 chemicals, 2 rings
c1ccc(-n2nccc2-n2cccc2)cc113 chemicals, 3 rings
4(1H)-Pyridinone, 1-phenyl-13 chemicals, 2 rings
Phenyl(2,3-dihydro-1H-pyrrolizin-5-yl)methanone13 chemicals, 3 rings![Scaffold O=c1cc(-c2ccccc2)cc[nH]1](/scaffold/DNUDULSSNHKPHP-UHFFFAOYSA-N/structure.svg)
4-Phenylpyridin-2-ol13 chemicals, 2 rings
O=C1CCCC2=C1C(c1ccccc1)C1=C(N2)c2ccccc2C1=O13 chemicals, 5 rings
O=C(CCS(=O)(=O)c1ccccc1)Nc1cccs113 chemicals, 2 rings
N-Cycloheptylbenzamide13 chemicals, 2 rings
O=C(NN=Cc1ccccc1)c1cccs113 chemicals, 2 rings![Scaffold O=c1[nH]cc(S(=O)(=O)N2CCCCC2)c(=O)[nH]1](/scaffold/DYUFKTRXVRQZPD-UHFFFAOYSA-N/structure.svg)
O=c1[nH]cc(S(=O)(=O)N2CCCCC2)c(=O)[nH]113 chemicals, 2 rings
O=C(c1conc1-c1ccccc1)N1CCN(c2ccccc2)CC113 chemicals, 4 rings
1-Phenyl-2-(4-phenylpiperazino)-1-ethanone13 chemicals, 3 rings
(1r,5s)-2-Azabicyclo[3.1.1]heptane13 chemicals, 3 rings
O=S(=O)(Nc1ccc2c(c1)OCCO2)c1ccccc113 chemicals, 3 rings
O=C(Nc1ccccc1)C1=CNc2ncnn2C1c1ccccc113 chemicals, 4 rings
5-(Phenoxymethyl)-1,3-oxazolidin-2-one13 chemicals, 2 rings
N=c1ccc2c(=O)n3ccccc3nc2n1Cc1ccco113 chemicals, 4 rings![Scaffold O=C(c1cc2ccccc2[nH]1)N1CCNCC1](/scaffold/FIVCRRVYLAXYFC-UHFFFAOYSA-N/structure.svg)
2-(Piperazin-1-ylcarbonyl)-1H-indole13 chemicals, 3 rings
1-Azaspiro(4.4)nonane13 chemicals, 2 rings
Oxanilide13 chemicals, 2 rings![Scaffold O=C1CCCc2[nH]ncc21](/scaffold/FUVZDXDCPRQZSQ-UHFFFAOYSA-N/structure.svg)
4,5,6,7-Tetrahydro-1H-indazol-4-one13 chemicals, 2 rings
1-Phenyl-2-(pyrimidin-2-ylthio)ethanone13 chemicals, 2 rings
1,1'-(Heptane-1,7-diyl)dibenzene13 chemicals, 2 rings
O=C(Cc1ccccc1)NCC1NCCS113 chemicals, 2 rings![Scaffold O=c1[nH]c(=O)c2[nH]c(N3CCOCC3)nc2[nH]1](/scaffold/HGORWYTZWOZUJO-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]c(N3CCOCC3)nc2[nH]113 chemicals, 3 rings![Scaffold O=c1[nH]c2ccccc2cc1CNc1ccccc1](/scaffold/HGRYSWBKUOITDA-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c2ccccc2cc1CNc1ccccc113 chemicals, 3 rings![Scaffold c1ccc2c(c1)ccc1cc[nH]c12](/scaffold/HIYWOHBEPVGIQN-UHFFFAOYSA-N/structure.svg)
1H-Benzo(g)indole13 chemicals, 3 rings![Scaffold O=C(NCc1ccc2[nH]ccc2c1)c1ccccc1](/scaffold/HKANSYLKPCMRFI-UHFFFAOYSA-N/structure.svg)
O=C(NCc1ccc2[nH]ccc2c1)c1ccccc113 chemicals, 3 rings
2-Morpholinoquinoline13 chemicals, 3 rings
Furo[2,3-b]quinoline13 chemicals, 3 rings